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PICNIC: an algorithm to predict absolute allelic copy number variation with microarray cancer data

High-throughput oligonucleotide microarrays are commonly employed to investigate genetic disease, including cancer. The algorithms employed to extract genotypes and copy number variation function optimally for diploid genomes usually associated with inherited disease. However, cancer genomes are ane...

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Main Authors: Greenman, Chris D., Bignell, Graham, Butler, Adam, Edkins, Sarah, Hinton, Jon, Beare, Dave, Swamy, Sajani, Santarius, Thomas, Chen, Lina, Widaa, Sara, Futreal, P. Andy, Stratton, Michael R.
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2010
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800165/
https://ncbi.nlm.nih.gov/pubmed/19837654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxp045
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