Amyloid-beta Isoform Metabolism Quantitation by Stable Isotope Labeled Kinetics

Por Mawuenyega, Kwasi G., Kasten, Tom, Sigurdson, Wendy, Bateman, Randall J.
Publicado em 2013

Stable isotope labeling tandem mass spectrometry (SILT): Integration with peptide identification and extension to data-dependent scans

Por Elbert, Donald L., Mawuenyega, Kwasi G., Scott, Evan A., Wildsmith, Kristin R., Bateman, Randall J.
Publicado em 2008

Decreased Clearance of CNS Amyloid-β in Alzheimer’s Disease

Por Mawuenyega, Kwasi G., Sigurdson, Wendy, Ovod, Vitaliy, Munsell, Ling, Kasten, Tom, Morris, John C., Yarasheski, Kevin E., Bateman, Randall J.
Publicado em 2010

Mycobacterium tuberculosis Functional Network Analysis by Global Subcellular Protein Profiling

Por Mawuenyega, Kwasi G., Forst, Christian V., Dobos, Karen M., Belisle, John T., Chen, Jin, Bradbury, E. Morton, Bradbury, Andrew R.M., Chen, Xian
Publicado em 2005

Associations Between β-Amyloid Kinetics and the β-Amyloid Diurnal Pattern in the Central Nervous System

Por Lucey, Brendan P., Mawuenyega, Kwasi G., Patterson, Bruce W., Elbert, Donald L., Ovod, Vitaliy, Kasten, Tom, Morris, John C., Bateman, Randall J
Publicado no JAMA Neurol (2017)

A single dose of the γ-secretase inhibitor semagacestat alters the cerebrospinal fluid peptidome in humans

Por Hölttä, Mikko, Dean, Robert A., Siemers, Eric, Mawuenyega, Kwasi G., Sigurdson, Wendy, May, Patrick C., Holtzman, David M., Portelius, Erik, Zetterberg, Henrik, Bateman, Randall J., Blennow, Kaj, Gobom, Johan
Publicado no Alzheimers Res Ther (2016)

Human Central Nervous System (CNS) ApoE Isoforms Are Increased by Age, Differentially Altered by Amyloidosis, and Relative Amounts Reversed in the CNS Compared with Plasma

Por Baker-Nigh, Alaina T., Mawuenyega, Kwasi G., Bollinger, James G., Ovod, Vitaliy, Kasten, Tom, Franklin, Erin E., Liao, Fan, Jiang, Hong, Holtzman, David, Cairns, Nigel J., Morris, John C., Bateman, Randall J.
Publicado no J Biol Chem (2016)

A gamma-secretase inhibitor decreases amyloid-beta production in the central nervous system

Por Bateman, Randall J., Siemers, Eric R., Mawuenyega, Kwasi G., Wen, Guolin, Browning, Karen R., Sigurdson, Wendy C., Yarasheski, Kevin E., Friedrich, Stuart W., DeMattos, Ronald B., May, Patrick C., Paul, Steven M., Holtzman, David M.
Publicado em 2009

Aβ(1-15/16) as a marker for γ-secretase inhibition in Alzheimer’s disease

Por Portelius, Erik, Zetterberg, Henrik, Dean, Robert A., Marcil, Alexandre, Bourgeois, Philippe, Nutu, Magdalena, Andreasson, Ulf, Siemers, Eric, Mawuenyega, Kwasi G., Sigurdson, Wendy C., May, Patrick C., Paul, Steven M., Holtzman, David M., Blennow, Kaj, Bateman, Randall J.
Publicado em 2012

In vivo kinetic approach reveals slow SOD1 turnover in the CNS

Por Crisp, Matthew J., Mawuenyega, Kwasi G., Patterson, Bruce W., Reddy, Naveen C., Chott, Robert, Self, Wade K., Weihl, Conrad C., Jockel-Balsarotti, Jennifer, Varadhachary, Arun S., Bucelli, Robert C., Yarasheski, Kevin E., Bateman, Randall J., Miller, Timothy M.
Publicado no J Clin Invest (2015)

Age and Amyloid Effects on Human CNS Amyloid-Beta Kinetics

Por Patterson, Bruce W., Elbert, Donald L., Mawuenyega, Kwasi G., Kasten, Tom, Ovod, Vitaliy, Ma, Shengmei, Xiong, Chengjie, Chott, Robert, Yarasheski, Kevin, Sigurdson, Wendy, Zhang, Lily, Goate, Alison, Phil, D., Benzinger, Tammie, Morris, John C., Holtzman, David, Bateman, Randall J.
Publicado no Ann Neurol (2015)

Amyloid-β efflux from the CNS into the plasma

Por Roberts, Kaleigh Filisa, Elbert, Donald L., Kasten, Tom P., Patterson, Bruce W., Sigurdson, Wendy C., Connors, Rose E., Ovod, Vitaliy, Munsell, Ling Y., Mawuenyega, Kwasi G., Miller-Thomas, Michelle M., Moran, Christopher J., Cross, Dewitte T., Derdeyn, Colin P., Bateman, Randall J.
Publicado no Ann Neurol (2014)

Human apoE isoforms differentially regulate brain amyloid-β peptide clearance

Por Castellano, Joseph M., Kim, Jungsu, Stewart, Floy R., Jiang, Hong, DeMattos, Ronald B., Patterson, Bruce W., Fagan, Anne M., Morris, John C., Mawuenyega, Kwasi G., Cruchaga, Carlos, Goate, Alison M., Bales, Kelly R., Paul, Steven M., Bateman, Randall J., Holtzman, David M.
Publicado em 2011

In Vivo Human Apolipoprotein E Isoform Fractional Turnover Rates in the CNS

Por Wildsmith, Kristin R., Basak, Jacob M., Patterson, Bruce W., Pyatkivskyy, Yuriy, Kim, Jungsu, Yarasheski, Kevin E., Wang, Jennifer X., Mawuenyega, Kwasi G., Jiang, Hong, Parsadanian, Maia, Yoon, Hyejin, Kasten, Tom, Sigurdson, Wendy C., Xiong, Chengjie, Goate, Alison, Holtzman, David M., Bateman, Randall J.
Publicado em 2012

Correction: In Vivo Human Apolipoprotein E Isoform Fractional Turnover Rates in the CNS

Por Wildsmith, Kristin R., Basak, Jacob M., Patterson, Bruce W., Pyatkivskyy, Yuriy, Kim, Jungsu, Yarasheski, Kevin E., Wang, Jennifer X., Mawuenyega, Kwasi G., Jiang, Hong, Parsadanian, Maia, Yoon, Hyejin, Kasten, Tom, Sigurdson, Wendy C., Xiong, Chengjie, Goate, Alison, Holtzman, David M., Bateman, Randall J.
Publicado em 2012