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Amyloid-beta Isoform Metabolism Quantitation by Stable Isotope Labeled Kinetics

Abundant evidence suggests a central role for the amyloid-β (Aβ) peptide in Alzheimer’s disease (AD) pathogenesis. Production and clearance of different Aβ isoforms have been established as targets of proposed disease-modifying therapeutic treatments of AD. However, previous studies used multiple se...

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Détails bibliographiques
Auteurs principaux: Mawuenyega, Kwasi G., Kasten, Tom, Sigurdson, Wendy, Bateman, Randall J.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749773/
https://ncbi.nlm.nih.gov/pubmed/23714261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2013.04.031
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