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Decreased Clearance of CNS Amyloid-β in Alzheimer’s Disease

Alzheimer’s disease is thought to be caused by an imbalance between amyloid-β (Aβ) production and clearance leading to Aβ accumulation in the Central Nervous System (CNS). Aβ production and clearance are key targets in the development of disease modifying therapeutic agents for Alzheimer’s disease....

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mawuenyega, Kwasi G., Sigurdson, Wendy, Ovod, Vitaliy, Munsell, Ling, Kasten, Tom, Morris, John C., Yarasheski, Kevin E., Bateman, Randall J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073454/
https://ncbi.nlm.nih.gov/pubmed/21148344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1197623
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