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Decreased Clearance of CNS Amyloid-β in Alzheimer’s Disease

Alzheimer’s disease is thought to be caused by an imbalance between amyloid-β (Aβ) production and clearance leading to Aβ accumulation in the Central Nervous System (CNS). Aβ production and clearance are key targets in the development of disease modifying therapeutic agents for Alzheimer’s disease....

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Bibliografski detalji
Glavni autori: Mawuenyega, Kwasi G., Sigurdson, Wendy, Ovod, Vitaliy, Munsell, Ling, Kasten, Tom, Morris, John C., Yarasheski, Kevin E., Bateman, Randall J.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073454/
https://ncbi.nlm.nih.gov/pubmed/21148344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1197623
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