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Decreased Clearance of CNS Amyloid-β in Alzheimer’s Disease

Alzheimer’s disease is thought to be caused by an imbalance between amyloid-β (Aβ) production and clearance leading to Aβ accumulation in the Central Nervous System (CNS). Aβ production and clearance are key targets in the development of disease modifying therapeutic agents for Alzheimer’s disease....

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Sonraí Bibleagrafaíochta
Main Authors: Mawuenyega, Kwasi G., Sigurdson, Wendy, Ovod, Vitaliy, Munsell, Ling, Kasten, Tom, Morris, John C., Yarasheski, Kevin E., Bateman, Randall J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073454/
https://ncbi.nlm.nih.gov/pubmed/21148344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1197623
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