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Decreased Clearance of CNS Amyloid-β in Alzheimer’s Disease
Alzheimer’s disease is thought to be caused by an imbalance between amyloid-β (Aβ) production and clearance leading to Aβ accumulation in the Central Nervous System (CNS). Aβ production and clearance are key targets in the development of disease modifying therapeutic agents for Alzheimer’s disease....
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3073454/ https://ncbi.nlm.nih.gov/pubmed/21148344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1197623 |
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