Associations Between β-Amyloid Kinetics and the β-Amyloid Diurnal Pattern in the Central Nervous System

IMPORTANCE: Recent studies found that the concentration of amyloid-β (Aβ) fluctuates with the sleep-wake cycle. Although the amplitude of this day/night pattern attenuates with age and amyloid deposition, the relationship of Aβ kinetics (production, turnover, and clearance) to this oscillation has n...

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Bibliografiska uppgifter
I publikationen:JAMA Neurol
Huvudupphovsmän: Lucey, Brendan P., Mawuenyega, Kwasi G., Patterson, Bruce W., Elbert, Donald L., Ovod, Vitaliy, Kasten, Tom, Morris, John C., Bateman, Randall J
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5305432/
https://ncbi.nlm.nih.gov/pubmed/27992627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2016.4202
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