Age and Amyloid Effects on Human CNS Amyloid-Beta Kinetics

OBJECTIVE: Age is the single greatest risk factor for Alzheimer’s disease with the incidence doubling every 5 years after age 65. However, our understanding of the mechanistic relationship between increasing age and the risk for Alzheimer’s disease is currently limited. We therefore sought to determ...

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Vydáno v:Ann Neurol
Hlavní autoři: Patterson, Bruce W., Elbert, Donald L., Mawuenyega, Kwasi G., Kasten, Tom, Ovod, Vitaliy, Ma, Shengmei, Xiong, Chengjie, Chott, Robert, Yarasheski, Kevin, Sigurdson, Wendy, Zhang, Lily, Goate, Alison, Phil, D., Benzinger, Tammie, Morris, John C., Holtzman, David, Bateman, Randall J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546566/
https://ncbi.nlm.nih.gov/pubmed/26040676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24454
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