A Test of the Cytosolic Apolipoprotein E Hypothesis Fails to Detect the Escape of Apolipoprotein E from the Endocytic Pathway into the Cytosol and Shows that Direct Expression of A...

Tekijä DeMattos, Ronald B., Thorngate, Fayanne E., Williams, David L.
Julkaisussa J Neurosci (1999)

Scavenger receptor class B, type I (SR-BI) is the major route for the delivery of high density lipoprotein cholesterol to the steroidogenic pathway in cultured mouse adrenocortic...

Tekijä Temel, Ryan E., Trigatti, Bernardo, DeMattos, Ronald B., Azhar, Salman, Krieger, Monty, Williams, David L.
Julkaistu 1997

Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease

Tekijä DeMattos, Ronald B., Bales, Kelly R., Cummins, David J., Dodart, Jean-Cosme, Paul, Steven M., Holtzman, David M.
Julkaistu 2001

Apolipoprotein E Markedly Facilitates Age-Dependent Cerebral Amyloid Angiopathy and Spontaneous Hemorrhage in Amyloid Precursor Protein Transgenic Mice

Tekijä Fryer, John D., Taylor, Jennie W., DeMattos, Ronald B., Bales, Kelly R., Paul, Steven M., Parsadanian, Maia, Holtzman, David M.
Julkaisussa J Neurosci (2003)

Midlife blood pressure, plasma β amyloid and the risk for Alzheimer’s disease: the Honolulu Asia Aging Study

Tekijä Shah, Nilay S., Vidal, Jean-Sébastien, Masaki, Kamal, Petrovitch, Helen, Ross, G. Webster, Tilley, Cathy, DeMattos, Ronald B., Tracy, Russell P., White, Lon R., Launer, Lenore J.
Julkaistu 2012

Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease

Tekijä DeMattos, Ronald B., O'dell, Mark A., Parsadanian, Maia, Taylor, Jennie W., Harmony, Judith A. K., Bales, Kelly R., Paul, Steven M., Aronow, Bruce J., Holtzman, David M.
Julkaistu 2002

Central pharmacodynamic activity of solanezumab in mild Alzheimer's disease dementia

Tekijä Willis, Brian A., Sundell, Karen, Lachno, D. Richard, Ferguson-Sells, Lisa R., Case, Michael G., Holdridge, Karen, DeMattos, Ronald B., Raskin, Joel, Siemers, Eric R., Dean, Robert A.
Julkaisussa Alzheimers Dement (N Y) (2018)

Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood Aβ clearance in a mouse model of β-amyloidosis

Tekijä Castellano, Joseph M., Deane, Rashid, Gottesdiener, Andrew J., Verghese, Philip B., Stewart, Floy R., West, Tim, Paoletti, Andrew C., Kasper, Tristan R., DeMattos, Ronald B., Zlokovic, Berislav V., Holtzman, David M.
Julkaistu 2012

Advancing combination therapy for Alzheimer's disease

Tekijä Salloway, Stephen P., Sevingy, Jeff, Budur, Kumar, Pederson, Jan Torleif, DeMattos, Ronald B., Von Rosenstiel, Philipp, Paez, Antonio, Evans, Rebecca, Weber, Christopher J., Hendrix, James A., Worley, Susan, Bain, Lisa J., Carrillo, Maria C.
Julkaisussa Alzheimers Dement (N Y) (2020)

A gamma-secretase inhibitor decreases amyloid-beta production in the central nervous system

Tekijä Bateman, Randall J., Siemers, Eric R., Mawuenyega, Kwasi G., Wen, Guolin, Browning, Karen R., Sigurdson, Wendy C., Yarasheski, Kevin E., Friedrich, Stuart W., DeMattos, Ronald B., May, Patrick C., Paul, Steven M., Holtzman, David M.
Julkaistu 2009

In Vivo Assessment of Brain Interstitial Fluid with Microdialysis Reveals Plaque-Associated Changes in Amyloid-β Metabolism and Half-Life

Tekijä Cirrito, John R., May, Patrick C., O'Dell, Mark A., Taylor, Jennie W., Parsadanian, Maia, Cramer, Jeffrey W., Audia, James E., Nissen, Jeffrey S., Bales, Kelly R., Paul, Steven M., DeMattos, Ronald B., Holtzman, David M.
Julkaisussa J Neurosci (2003)

TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques

Tekijä Wang, Yaming, Ulland, Tyler K., Ulrich, Jason D., Song, Wilbur, Tzaferis, John A., Hole, Justin T., Yuan, Peng, Mahan, Thomas E., Shi, Yang, Gilfillan, Susan, Cella, Marina, Grutzendler, Jaime, DeMattos, Ronald B., Cirrito, John R., Holtzman, David M., Colonna, Marco
Julkaisussa J Exp Med (2016)

Human apoE isoforms differentially regulate brain amyloid-β peptide clearance

Tekijä Castellano, Joseph M., Kim, Jungsu, Stewart, Floy R., Jiang, Hong, DeMattos, Ronald B., Patterson, Bruce W., Fagan, Anne M., Morris, John C., Mawuenyega, Kwasi G., Cruchaga, Carlos, Goate, Alison M., Bales, Kelly R., Paul, Steven M., Bateman, Randall J., Holtzman, David M.
Julkaistu 2011

Exacerbation of Cerebral Amyloid Angiopathy-Associated Microhemorrhage in Amyloid Precursor Protein Transgenic Mice by Immunotherapy Is Dependent on Antibody Recognition of Deposit...

Tekijä Racke, Margaret M., Boone, Laura I., Hepburn, Deena L., Parsadainian, Maia, Bryan, Matthew T., Ness, Daniel K., Piroozi, Kathy S., Jordan, William H., Brown, Donna D., Hoffman, Wherly P., Holtzman, David M., Bales, Kelly R., Gitter, Bruce D., May, Patrick C., Paul, Steven M., DeMattos, Ronald B.
Julkaisussa J Neurosci (2005)