Novel roles for JNK1 in metabolism

by Belgardt, Bengt F., Mauer, Jan, Brüning, Jens C.
Published 2010

Phosphoinositide-Dependent Kinase 1 Provides Negative Feedback Inhibition to Toll-Like Receptor-Mediated NF-κB Activation in Macrophages

by Chaurasia, Bhagirath, Mauer, Jan, Koch, Linda, Goldau, Julia, Kock, Anja-Sterner, Brüning, Jens C.
Published 2010

Hierarchical prediction errors in midbrain and septum during social learning

by Diaconescu, Andreea O., Mathys, Christoph, Weber, Lilian A. E., Kasper, Lars, Mauer, Jan, Stephan, Klaas E.
Published in Soc Cogn Affect Neurosci (2017)

Single copy shRNA configuration for ubiquitous gene knockdown in mice

by Seibler, Jost, Küter-Luks, Birgit, Kern, Heidrun, Streu, Sandra, Plum, Leona, Mauer, Jan, Kühn, Ralf, Brüning, Jens C., Schwenk, Frieder
Published 2005

Myeloid Cell-Restricted Insulin Receptor Deficiency Protects Against Obesity-Induced Inflammation and Systemic Insulin Resistance

by Mauer, Jan, Chaurasia, Bhagirath, Plum, Leona, Quast, Thomas, Hampel, Brigitte, Blüher, Matthias, Kolanus, Waldemar, Kahn, C. Ronald, Brüning, Jens C.
Published 2010

MyD88 signaling in the CNS is required for development of fatty acid induced leptin resistance and diet-induced obesity

by Kleinridders, André, Schenten, Dominik, Könner, A. Christine, Belgardt, Bengt F., Mauer, Jan, Okamura, Tomoo, Wunderlich, F. Thomas, Medzhitov, Ruslan, Brüning, Jens C.
Published 2009

A scalable CRISPR/Cas9-based fluorescent reporter assay to study DNA double-strand break repair choice

by Roidos, Paris, Sungalee, Stephanie, Benfatto, Salvatore, Serçin, Özdemirhan, Stütz, Adrian M., Abdollahi, Amir, Mauer, Jan, Zenke, Frank T., Korbel, Jan O., Mardin, Balca R.
Published in Nat Commun (2020)

Hypothalamic and pituitary c-Jun N-terminal kinase 1 signaling coordinately regulates glucose metabolism

by Belgardt, Bengt F., Mauer, Jan, Wunderlich, F. Thomas, Ernst, Marianne B., Pal, Martin, Spohn, Gabriele, Brönneke, Hella S., Brodesser, Susanne, Hampel, Brigitte, Schauss, Astrid C., Brüning, Jens C.
Published 2010

FTO controls reversible m(6)Am RNA methylation during snRNA biogenesis

by Mauer, Jan, Sindelar, Miriam, Despic, Vladimir, Guez, Théo, Hawley, Ben R., Vasseur, Jean-Jacques, Rentmeister, Andrea, Gross, Steven S., Pellizzoni, Livio, Debart, Françoise, Goodarzi, Hani, Jaffrey, Samie R.
Published in Nat Chem Biol (2019)

An Obesity-Predisposing Variant of the FTO Gene Regulates D2R-Dependent Reward Learning

by Sevgi, Meltem, Rigoux, Lionel, Kühn, Anne B., Mauer, Jan, Schilbach, Leonhard, Hess, Martin E., Gruendler, Theo O.J., Ullsperger, Markus, Stephan, Klaas Enno, Brüning, Jens C., Tittgemeyer, Marc
Published in J Neurosci (2015)

Neonatal insulin action impairs hypothalamic neurocircuit formation in response to maternal high fat feeding

by Vogt, Merly C., Paeger, Lars, Hess, Simon, Steculorum, Sophie M., Awazawa, Motoharu, Hampel, Brigitte, Neupert, Susanne, Nicholls, Hayley T., Mauer, Jan, Hausen, A. Christine, Predel, Reinhard, Kloppenburg, Peter, Horvath, Tamas L., Brüning, Jens C.
Published 2014

Obesity exacerbates colitis-associated cancer via IL-6-regulated macrophage polarisation and CCL-20/CCR-6-mediated lymphocyte recruitment

by Wunderlich, Claudia M., Ackermann, P. Justus, Ostermann, Anna Lena, Adams-Quack, Petra, Vogt, Merly C., Tran, My-Ly, Nikolajev, Alexei, Waisman, Ari, Garbers, Christoph, Theurich, Sebastian, Mauer, Jan, Hövelmeyer, Nadine, Wunderlich, F. Thomas
Published in Nat Commun (2018)

Reversible methylation of m(6)A(m) in the 5′ cap controls mRNA stability

by Mauer, Jan, Luo, Xiaobing, Blanjoie, Alexandre, Jiao, Xinfu, Grozhik, Anya V., Patil, Deepak P., Linder, Bastian, Pickering, Brian F., Vasseur, Jean-Jacques, Chen, Qiuying, Gross, Steven S., Elemento, Olivier, Debart, Françoise, Kiledjian, Megerditch, Jaffrey, Samie R.
Published in Nature (2016)

Loss of UCP2 Attenuates Mitochondrial Dysfunction without Altering ROS Production and Uncoupling Activity

by Kukat, Alexandra, Dogan, Sukru Anil, Edgar, Daniel, Mourier, Arnaud, Jacoby, Christoph, Maiti, Priyanka, Mauer, Jan, Becker, Christina, Senft, Katharina, Wibom, Rolf, Kudin, Alexei P., Hultenby, Kjell, Flögel, Ulrich, Rosenkranz, Stephan, Ricquier, Daniel, Kunz, Wolfram S., Trifunovic, Aleksandra
Published 2014

Hepatic Bax Inhibitor-1 Inhibits IRE1α and Protects from Obesity-associated Insulin Resistance and Glucose Intolerance

by Bailly-Maitre, Béatrice, Belgardt, Bengt F., Jordan, Sabine D., Coornaert, Beatrice, John von Freyend, Miriam, Kleinridders, Andre, Mauer, Jan, Cuddy, Michael, Kress, Christina L., Willmes, Diana, Essig, Manuela, Hampel, Brigitte, Protzer, Ulrike, Reed, John C., Brüning, Jens C.
Published 2010

Interleukin-6 signaling promotes alternative macrophage activation to limit obesity-associated insulin resistance and endotoxemia

by Mauer, Jan, Chaurasia, Bhagirath, Goldau, Julia, Vogt, Merly C., Ruud, Johan, Nguyen, Khoa D., Theurich, Sebastian, Hausen, A. Christine, Schmitz, Joel, Brönneke, Hella S., Estevez, Emma, Allen, Tamara L., Mesaros, Andrea, Partridge, Linda, Febbraio, Mark A., Chawla, Ajay, Wunderlich, F. Thomas, Brüning, Jens C.
Published 2014

AgRP Neurons Control Systemic Insulin Sensitivity via Myostatin Expression in Brown Adipose Tissue

by Steculorum, Sophie M., Ruud, Johan, Karakasilioti, Ismene, Backes, Heiko, Ruud, Linda Engström, Timper, Katharina, Hess, Martin E., Tsaousidou, Eva, Mauer, Jan, Vogt, Merly C., Paeger, Lars, Bremser, Stephan, Klein, Andreas C., Morgan, Donald A., Frommolt, Peter, Brinkkötter, Paul T., Hammerschmidt, Philipp, Benzing, Thomas, Rahmouni, Kamal, Wunderlich, F. Thomas, Kloppenburg, Peter, Brüning, Jens C.
Published in Cell (2016)