Cox-dependent fatty acid metabolites cause pain through activation of the irritant receptor TRPA1

per Materazzi, Serena, Nassini, Romina, Andrè, Eunice, Campi, Barbara, Amadesi, Silvia, Trevisani, Marcello, Bunnett, Nigel W., Patacchini, Riccardo, Geppetti, Pierangelo
Publicat 2008

Functional Characterization of Human ProNGF and NGF Mutants: Identification of NGF P61SR100E as a “Painless” Lead Investigational Candidate for Therapeutic Applications

per Malerba, Francesca, Paoletti, Francesca, Bruni Ercole, Bruno, Materazzi, Serena, Nassini, Romina, Coppi, Elisabetta, Patacchini, Riccardo, Capsoni, Simona, Lamba, Doriano, Cattaneo, Antonino
Publicat a PLoS One (2015)

TRPA1 mediates the antinociceptive properties of the constituent of Crocus sativus L., safranal

per Li Puma, Simone, Landini, Lorenzo, Macedo, Sergio J., Seravalli, Viola, Marone, Ilaria M., Coppi, Elisabetta, Patacchini, Riccardo, Geppetti, Pierangelo, Materazzi, Serena, Nassini, Romina, De Logu, Francesco
Publicat a J Cell Mol Med (2019)

The anti‐migraine component of butterbur extracts, isopetasin, desensitizes peptidergic nociceptors by acting on TRPA1 cation channel

per Benemei, Silvia, De Logu, Francesco, Li Puma, Simone, Marone, Ilaria Maddalena, Coppi, Elisabetta, Ugolini, Filippo, Liedtke, Wolfgang, Pollastro, Federica, Appendino, Giovanni, Geppetti, Pierangelo, Materazzi, Serena, Nassini, Romina
Publicat a Br J Pharmacol (2017)

Transient receptor potential ankyrin 1 contributes to somatic pain hypersensitivity in experimental colitis

per Jain, Piyush, Materazzi, Serena, De Logu, Francesco, Rossi Degl’Innocenti, Duccio, Fusi, Camilla, Li Puma, Simone, Marone, Ilaria M., Coppi, Elisabetta, Holzer, Peter, Geppetti, Pierangelo, Nassini, Romina
Publicat a Sci Rep (2020)

The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives

per Nassini, Romina, Fusi, Camilla, Materazzi, Serena, Coppi, Elisabetta, Tuccinardi, Tiziano, Marone, Ilaria M, De Logu, Francesco, Preti, Delia, Tonello, Raquel, Chiarugi, Alberto, Patacchini, Riccardo, Geppetti, Pierangelo, Benemei, Silvia
Publicat a Br J Pharmacol (2015)

TRPA1/NOX in the soma of trigeminal ganglion neurons mediates migraine-related pain of glyceryl trinitrate in mice

per Marone, Ilaria Maddalena, De Logu, Francesco, Nassini, Romina, De Carvalho Goncalves, Muryel, Benemei, Silvia, Ferreira, Juliano, Jain, Piyush, Li Puma, Simone, Bunnett, Nigel W, Geppetti, Pierangelo, Materazzi, Serena
Publicat a Brain (2018)

Critical role of calcitonin gene-related peptide receptors in cortical spreading depression

per Tozzi, Alessandro, de Iure, Antonio, Di Filippo, Massimiliano, Costa, Cinzia, Caproni, Stefano, Pisani, Antonio, Bonsi, Paola, Picconi, Barbara, Cupini, Letizia M., Materazzi, Serena, Geppetti, Pierangelo, Sarchielli, Paola, Calabresi, Paolo
Publicat 2012

ACTIVATION OF TRPA1 ON DURAL AFFERENTS: A POTENTIAL MECHANISM OF HEADACHE PAIN

per Edelmayer, Rebecca M., Le, Larry N., Yan, Jin, Wei, Xiaomei, Nassini, Romina, Materazzi, Serena, Preti, Delia, Appendino, Giovanni, Geppetti, Pierangelo, Dodick, David W., Vanderah, Todd W., Porreca, Frank, Dussor, Gregory
Publicat 2012

The peptide Phα1β, from spider venom, acts as a TRPA1 channel antagonist with antinociceptive effects in mice

per Tonello, Raquel, Fusi, Camilla, Materazzi, Serena, Marone, Ilaria M, De Logu, Francesco, Benemei, Silvia, Gonçalves, Muryel C, Coppi, Elisabetta, Castro‐Junior, Celio J, Gomez, Marcus Vinicius, Geppetti, Pierangelo, Ferreira, Juliano, Nassini, Romina
Publicat a Br J Pharmacol (2016)

4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1

per Trevisani, Marcello, Siemens, Jan, Materazzi, Serena, Bautista, Diana M., Nassini, Romina, Campi, Barbara, Imamachi, Noritaka, Andrè, Eunice, Patacchini, Riccardo, Cottrell, Graeme S., Gatti, Raffaele, Basbaum, Allan I., Bunnett, Nigel W., Julius, David, Geppetti, Pierangelo
Publicat 2007

Cigarette smoke–induced neurogenic inflammation is mediated by α,β-unsaturated aldehydes and the TRPA1 receptor in rodents

per Andrè, Eunice, Campi, Barbara, Materazzi, Serena, Trevisani, Marcello, Amadesi, Silvia, Massi, Daniela, Creminon, Christophe, Vaksman, Natalya, Nassini, Romina, Civelli, Maurizio, Baraldi, Pier Giovanni, Poole, Daniel P., Bunnett, Nigel W., Geppetti, Pierangelo, Patacchini, Riccardo
Publicat 2008

The blockade of transient receptor potential ankirin 1 (TRPA1) signalling mediates antidepressant- and anxiolytic-like actions in mice

per de Moura, Juliana Cavalcante, Noroes, Maíra Macedo, Rachetti, Vanessa de Paula Soares, Soares, Bruno Lobão, Preti, Delia, Nassini, Romina, Materazzi, Serena, Marone, Ilaria Maddalena, Minocci, Daiana, Geppetti, Pierangelo, Gavioli, Elaine Cristina, André, Eunice
Publicat a Br J Pharmacol (2014)

Steroidal and non-steroidal third-generation aromatase inhibitors induce pain-like symptoms via TRPA1

per Fusi, Camilla, Materazzi, Serena, Benemei, Silvia, Coppi, Elisabetta, Trevisan, Gabriela, Marone, Ilaria M., Minocci, Daiana, De Logu, Francesco, Tuccinardi, Tiziano, Di Tommaso, Maria Rosaria, Susini, Tommaso, Moneti, Gloriano, Pieraccini, Giuseppe, Geppetti, Pierangelo, Nassini, Romina
Publicat a Nat Commun (2014)

Parthenolide inhibits nociception and neurogenic vasodilatation in the trigeminovascular system by targeting TRPA1 channel

per Materazzi, Serena, Benemei, Silvia, Fusi, Camilla, Gualdani, Roberta, De Siena, Gaetano, Vastani, Nisha, Andersson, David A., Trevisan, Gabriela, Moncelli, Maria Rosa, Wei, Xiaomei, Dussor, Gregory, Pollastro, Federica, Patacchini, Riccardo, Appendino, Giovanni, Geppetti, Pierangelo, Nassini, Romina
Publicat 2013

Transient Receptor Potential Ankyrin 1 Channel Localized to Non-Neuronal Airway Cells Promotes Non-Neurogenic Inflammation

per Nassini, Romina, Pedretti, Pamela, Moretto, Nadia, Fusi, Camilla, Carnini, Chiara, Facchinetti, Fabrizio, Viscomi, Arturo Roberto, Pisano, Anna Rita, Stokesberry, Susan, Brunmark, Charlott, Svitacheva, Naila, McGarvey, Lorcan, Patacchini, Riccardo, Damholt, Anders B., Geppetti, Pierangelo, Materazzi, Serena
Publicat 2012

Oxidative stress mediates thalidomide-induced pain by targeting peripheral TRPA1 and central TRPV4

per De Logu, Francesco, Trevisan, Gabriela, Marone, Ilaria Maddalena, Coppi, Elisabetta, Padilha Dalenogare, Diéssica, Titiz, Mustafa, Marini, Matilde, Landini, Lorenzo, Souza Monteiro de Araujo, Daniel, Li Puma, Simone, Materazzi, Serena, De Siena, Gaetano, Geppetti, Pierangelo, Nassini, Romina
Publicat a BMC Biol (2020)

Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice

per De Logu, Francesco, Nassini, Romina, Materazzi, Serena, Carvalho Gonçalves, Muryel, Nosi, Daniele, Rossi Degl’Innocenti, Duccio, Marone, Ilaria M., Ferreira, Juliano, Li Puma, Simone, Benemei, Silvia, Trevisan, Gabriela, Souza Monteiro de Araújo, Daniel, Patacchini, Riccardo, Bunnett, Nigel W., Geppetti, Pierangelo
Publicat a Nat Commun (2017)

Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice

per Grant, Andrew D, Cottrell, Graeme S, Amadesi, Silvia, Trevisani, Marcello, Nicoletti, Paola, Materazzi, Serena, Altier, Christophe, Cenac, Nicolas, Zamponi, Gerald W, Bautista-Cruz, Francisco, Lopez, Carlos Barajas, Joseph, Elizabeth K, Levine, Jon D, Liedtke, Wolfgang, Vanner, Stephen, Vergnolle, Nathalie, Geppetti, Pierangelo, Bunnett, Nigel W
Publicat 2007

The TGR5 receptor mediates bile acid–induced itch and analgesia

per Alemi, Farzad, Kwon, Edwin, Poole, Daniel P., Lieu, TinaMarie, Lyo, Victoria, Cattaruzza, Fiore, Cevikbas, Ferda, Steinhoff, Martin, Nassini, Romina, Materazzi, Serena, Guerrero-Alba, Raquel, Valdez-Morales, Eduardo, Cottrell, Graeme S., Schoonjans, Kristina, Geppetti, Pierangelo, Vanner, Stephen J., Bunnett, Nigel W., Corvera, Carlos U.
Publicat 2013