The blockade of transient receptor potential ankirin 1 (TRPA1) signalling mediates antidepressant- and anxiolytic-like actions in mice

BACKGROUND AND PURPOSE: Transient receptor potential vanilloid 1 (TRPV1) and TRP ankyrin 1 (TRPA1) are involved in many biological processes, including nociception and hyperalgesia. Whereas the involvement of TRPV1 in psychiatric disorders such as anxiety and depression has been reported, little is...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: de Moura, Juliana Cavalcante, Noroes, Maíra Macedo, Rachetti, Vanessa de Paula Soares, Soares, Bruno Lobão, Preti, Delia, Nassini, Romina, Materazzi, Serena, Marone, Ilaria Maddalena, Minocci, Daiana, Geppetti, Pierangelo, Gavioli, Elaine Cristina, André, Eunice
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241094/
https://ncbi.nlm.nih.gov/pubmed/24846744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12786
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