The blockade of transient receptor potential ankirin 1 (TRPA1) signalling mediates antidepressant- and anxiolytic-like actions in mice

BACKGROUND AND PURPOSE: Transient receptor potential vanilloid 1 (TRPV1) and TRP ankyrin 1 (TRPA1) are involved in many biological processes, including nociception and hyperalgesia. Whereas the involvement of TRPV1 in psychiatric disorders such as anxiety and depression has been reported, little is...

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Dettagli Bibliografici
Pubblicato in:Br J Pharmacol
Autori principali: de Moura, Juliana Cavalcante, Noroes, Maíra Macedo, Rachetti, Vanessa de Paula Soares, Soares, Bruno Lobão, Preti, Delia, Nassini, Romina, Materazzi, Serena, Marone, Ilaria Maddalena, Minocci, Daiana, Geppetti, Pierangelo, Gavioli, Elaine Cristina, André, Eunice
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2014
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Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241094/
https://ncbi.nlm.nih.gov/pubmed/24846744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12786
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