Cox-dependent fatty acid metabolites cause pain through activation of the irritant receptor TRPA1

Por Materazzi, Serena, Nassini, Romina, Andrè, Eunice, Campi, Barbara, Amadesi, Silvia, Trevisani, Marcello, Bunnett, Nigel W., Patacchini, Riccardo, Geppetti, Pierangelo
Publicado em 2008

Functional Characterization of Human ProNGF and NGF Mutants: Identification of NGF P61SR100E as a “Painless” Lead Investigational Candidate for Therapeutic Applications

Por Malerba, Francesca, Paoletti, Francesca, Bruni Ercole, Bruno, Materazzi, Serena, Nassini, Romina, Coppi, Elisabetta, Patacchini, Riccardo, Capsoni, Simona, Lamba, Doriano, Cattaneo, Antonino
Publicado no PLoS One (2015)

Norepinephrine promotes tumor microenvironment reactivity through β3-adrenoreceptors during melanoma progression

Por Calvani, Maura, Pelon, Floriane, Comito, Giuseppina, Taddei, Maria Letizia, Moretti, Silvia, Innocenti, Stefania, Nassini, Romina, Gerlini, Gianni, Borgognoni, Lorenzo, Bambi, Franco, Giannoni, Elisa, Filippi, Luca, Chiarugi, Paola
Publicado no Oncotarget (2014)

The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives

Por Nassini, Romina, Fusi, Camilla, Materazzi, Serena, Coppi, Elisabetta, Tuccinardi, Tiziano, Marone, Ilaria M, De Logu, Francesco, Preti, Delia, Tonello, Raquel, Chiarugi, Alberto, Patacchini, Riccardo, Geppetti, Pierangelo, Benemei, Silvia
Publicado no Br J Pharmacol (2015)

ACTIVATION OF TRPA1 ON DURAL AFFERENTS: A POTENTIAL MECHANISM OF HEADACHE PAIN

Por Edelmayer, Rebecca M., Le, Larry N., Yan, Jin, Wei, Xiaomei, Nassini, Romina, Materazzi, Serena, Preti, Delia, Appendino, Giovanni, Geppetti, Pierangelo, Dodick, David W., Vanderah, Todd W., Porreca, Frank, Dussor, Gregory
Publicado em 2012

The peptide Phα1β, from spider venom, acts as a TRPA1 channel antagonist with antinociceptive effects in mice

Por Tonello, Raquel, Fusi, Camilla, Materazzi, Serena, Marone, Ilaria M, De Logu, Francesco, Benemei, Silvia, Gonçalves, Muryel C, Coppi, Elisabetta, Castro‐Junior, Celio J, Gomez, Marcus Vinicius, Geppetti, Pierangelo, Ferreira, Juliano, Nassini, Romina
Publicado no Br J Pharmacol (2016)

4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1

Por Trevisani, Marcello, Siemens, Jan, Materazzi, Serena, Bautista, Diana M., Nassini, Romina, Campi, Barbara, Imamachi, Noritaka, Andrè, Eunice, Patacchini, Riccardo, Cottrell, Graeme S., Gatti, Raffaele, Basbaum, Allan I., Bunnett, Nigel W., Julius, David, Geppetti, Pierangelo
Publicado em 2007

Cigarette smoke–induced neurogenic inflammation is mediated by α,β-unsaturated aldehydes and the TRPA1 receptor in rodents

Por Andrè, Eunice, Campi, Barbara, Materazzi, Serena, Trevisani, Marcello, Amadesi, Silvia, Massi, Daniela, Creminon, Christophe, Vaksman, Natalya, Nassini, Romina, Civelli, Maurizio, Baraldi, Pier Giovanni, Poole, Daniel P., Bunnett, Nigel W., Geppetti, Pierangelo, Patacchini, Riccardo
Publicado em 2008

The blockade of transient receptor potential ankirin 1 (TRPA1) signalling mediates antidepressant- and anxiolytic-like actions in mice

Por de Moura, Juliana Cavalcante, Noroes, Maíra Macedo, Rachetti, Vanessa de Paula Soares, Soares, Bruno Lobão, Preti, Delia, Nassini, Romina, Materazzi, Serena, Marone, Ilaria Maddalena, Minocci, Daiana, Geppetti, Pierangelo, Gavioli, Elaine Cristina, André, Eunice
Publicado no Br J Pharmacol (2014)

Steroidal and non-steroidal third-generation aromatase inhibitors induce pain-like symptoms via TRPA1

Por Fusi, Camilla, Materazzi, Serena, Benemei, Silvia, Coppi, Elisabetta, Trevisan, Gabriela, Marone, Ilaria M., Minocci, Daiana, De Logu, Francesco, Tuccinardi, Tiziano, Di Tommaso, Maria Rosaria, Susini, Tommaso, Moneti, Gloriano, Pieraccini, Giuseppe, Geppetti, Pierangelo, Nassini, Romina
Publicado no Nat Commun (2014)

PD-L1 up-regulation in melanoma increases disease aggressiveness and is mediated through miR-17-5p

Por Audrito, Valentina, Serra, Sara, Stingi, Aureliano, Orso, Francesca, Gaudino, Federica, Bologna, Cinzia, Neri, Francesco, Garaffo, Giulia, Nassini, Romina, Baroni, Gianna, Rulli, Eliana, Massi, Daniela, Oliviero, Salvatore, Piva, Roberto, Taverna, Daniela, Mandalà, Mario, Deaglio, Silvia
Publicado no Oncotarget (2017)

Parthenolide inhibits nociception and neurogenic vasodilatation in the trigeminovascular system by targeting TRPA1 channel

Por Materazzi, Serena, Benemei, Silvia, Fusi, Camilla, Gualdani, Roberta, De Siena, Gaetano, Vastani, Nisha, Andersson, David A., Trevisan, Gabriela, Moncelli, Maria Rosa, Wei, Xiaomei, Dussor, Gregory, Pollastro, Federica, Patacchini, Riccardo, Appendino, Giovanni, Geppetti, Pierangelo, Nassini, Romina
Publicado em 2013

Transient Receptor Potential Ankyrin 1 Channel Localized to Non-Neuronal Airway Cells Promotes Non-Neurogenic Inflammation

Por Nassini, Romina, Pedretti, Pamela, Moretto, Nadia, Fusi, Camilla, Carnini, Chiara, Facchinetti, Fabrizio, Viscomi, Arturo Roberto, Pisano, Anna Rita, Stokesberry, Susan, Brunmark, Charlott, Svitacheva, Naila, McGarvey, Lorcan, Patacchini, Riccardo, Damholt, Anders B., Geppetti, Pierangelo, Materazzi, Serena
Publicado em 2012

The TGR5 receptor mediates bile acid–induced itch and analgesia

Por Alemi, Farzad, Kwon, Edwin, Poole, Daniel P., Lieu, TinaMarie, Lyo, Victoria, Cattaruzza, Fiore, Cevikbas, Ferda, Steinhoff, Martin, Nassini, Romina, Materazzi, Serena, Guerrero-Alba, Raquel, Valdez-Morales, Eduardo, Cottrell, Graeme S., Schoonjans, Kristina, Geppetti, Pierangelo, Vanner, Stephen J., Bunnett, Nigel W., Corvera, Carlos U.
Publicado em 2013

The Bile Acid Receptor TGR5 Activates the TRPA1 Channel to Induce Itch in Mice

Por Lieu, TinaMarie, Jayaweera, Gihan, Zhao, Peishen, Poole, Daniel P., Jensen, Dane, Grace, Megan, McIntyre, Peter, Bron, Romke, Wilson, Yvette M., Krappitz, Matteus, Haerteis, Silke, Korbmacher, Christoph, Steinhoff, Martin S., Nassini, Romina, Materazzi, Serena, Geppetti, Pierangelo, Corvera, Carlos U., Bunnett, Nigel W.
Publicado no Gastroenterology (2014)