The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives

BACKGROUND AND PURPOSE: Although still used by hundreds of millions of people worldwide, the mechanism of the analgesic action of the pyrazolone derivatives (PDs), dipyrone, propyphenazone and antipyrine remains unknown. The transient receptor potential ankyrin 1 (TRPA1) channel, expressed by nocice...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Br J Pharmacol
Päätekijät: Nassini, Romina, Fusi, Camilla, Materazzi, Serena, Coppi, Elisabetta, Tuccinardi, Tiziano, Marone, Ilaria M, De Logu, Francesco, Preti, Delia, Tonello, Raquel, Chiarugi, Alberto, Patacchini, Riccardo, Geppetti, Pierangelo, Benemei, Silvia
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley & Sons, Ltd 2015
Aiheet:
Research Papers
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500374/
https://ncbi.nlm.nih.gov/pubmed/25765567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13129
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