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The anti‐migraine component of butterbur extracts, isopetasin, desensitizes peptidergic nociceptors by acting on TRPA1 cation channel
BACKGROUND AND PURPOSE: The mechanism of the anti‐migraine action of extracts of butterbur [Petasites hybridus (L.) Gaertn.] is unknown. Here, we investigated the ability of isopetasin, a major constituent of these extracts, to specifically target TRPA1 channel and to affect functional responses rel...
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| 出版年: | Br J Pharmacol |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5554318/ https://ncbi.nlm.nih.gov/pubmed/28622417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13917 |
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