The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives

BACKGROUND AND PURPOSE: Although still used by hundreds of millions of people worldwide, the mechanism of the analgesic action of the pyrazolone derivatives (PDs), dipyrone, propyphenazone and antipyrine remains unknown. The transient receptor potential ankyrin 1 (TRPA1) channel, expressed by nocice...

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書目詳細資料
發表在:Br J Pharmacol
Main Authors: Nassini, Romina, Fusi, Camilla, Materazzi, Serena, Coppi, Elisabetta, Tuccinardi, Tiziano, Marone, Ilaria M, De Logu, Francesco, Preti, Delia, Tonello, Raquel, Chiarugi, Alberto, Patacchini, Riccardo, Geppetti, Pierangelo, Benemei, Silvia
格式: Artigo
語言:Inglês
出版: John Wiley & Sons, Ltd 2015
主題:
Research Papers
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500374/
https://ncbi.nlm.nih.gov/pubmed/25765567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13129
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