PD-L1 up-regulation in melanoma increases disease aggressiveness and is mediated through miR-17-5p

PD-L1 is expressed by a subset of patients with metastatic melanoma (MM) with an unfavorable outcome. Its expression is increased in cells resistant to BRAF or MEK inhibitors (BRAFi or MEKi). However, the function and regulation of expression of PD-L1 remain incompletely understood. After generating...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Audrito, Valentina, Serra, Sara, Stingi, Aureliano, Orso, Francesca, Gaudino, Federica, Bologna, Cinzia, Neri, Francesco, Garaffo, Giulia, Nassini, Romina, Baroni, Gianna, Rulli, Eliana, Massi, Daniela, Oliviero, Salvatore, Piva, Roberto, Taverna, Daniela, Mandalà, Mario, Deaglio, Silvia
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362532/
https://ncbi.nlm.nih.gov/pubmed/28199980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15213
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