Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice

It is known that transient receptor potential ankyrin 1 (TRPA1) channels, expressed by nociceptors, contribute to neuropathic pain. Here we show that TRPA1 is also expressed in Schwann cells. We found that in mice with partial sciatic nerve ligation, TRPA1 silencing in nociceptors attenuated mechani...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: De Logu, Francesco, Nassini, Romina, Materazzi, Serena, Carvalho Gonçalves, Muryel, Nosi, Daniele, Rossi Degl’Innocenti, Duccio, Marone, Ilaria M., Ferreira, Juliano, Li Puma, Simone, Benemei, Silvia, Trevisan, Gabriela, Souza Monteiro de Araújo, Daniel, Patacchini, Riccardo, Bunnett, Nigel W., Geppetti, Pierangelo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709495/
https://ncbi.nlm.nih.gov/pubmed/29192190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01739-2
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller