Schwann cells expressing nociceptive channel TRPA1 orchestrate ethanol-evoked neuropathic pain in mice

Excessive alcohol consumption is associated with spontaneous burning pain, hyperalgesia, and allodynia. Although acetaldehyde has been implicated in the painful alcoholic neuropathy, the mechanism by which the ethanol metabolite causes pain symptoms is unknown. Acute ethanol ingestion caused delayed...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: De Logu, Francesco, Li Puma, Simone, Landini, Lorenzo, Portelli, Francesca, Innocenti, Alessandro, de Araujo, Daniel Souza Monteiro, Janal, Malvin N., Patacchini, Riccardo, Bunnett, Nigel W., Geppetti, Pierangelo, Nassini, Romina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877331/
https://ncbi.nlm.nih.gov/pubmed/31487269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI128022
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