Analysis of N- and O-Glycosylation of Lysosomal Glycoproteins

door Tokhtaeva, Elmira, Mareninova, Olga A., Gukovskaya, Anna S., Vagin, Olga
Gepubliceerd in Methods Mol Biol (2017)

Impaired Autophagy and Organellar Dysfunction in Pancreatitis

door Gukovsky, Ilya, Pandol, Stephen J., Mareninova, Olga A., Shalbueva, Natalia, Jia, Wenzhuo, Gukovskaya, Anna S.
Gepubliceerd in 2012

Investigating the Pathobiology of Alcoholic Pancreatitis

door Pandol, Stephen J., Lugea, Aurelia, Mareninova, Olga A., Smoot, Duane, Gorelick, Fred S., Gukovskaya, Anna S., Gukovsky, Ilya
Gepubliceerd in 2011

Effects of Oxidative Alcohol Metabolism on the Mitochondrial Permeability Transition Pore and Necrosis in a Mouse Model of Alcoholic Pancreatitis

door SHALBUEVA, NATALIA, MARENINOVA, OLGA A., GERLOFF, ANDREAS, YUAN, JINGZHEN, WALDRON, RICHARD T., PANDOL, STEPHEN J., GUKOVSKAYA, ANNA S.
Gepubliceerd in 2012

Inflammatory cells regulate p53 and caspases in acute pancreatitis

door Nakamura, Yuji, Do, Jae Hyuk, Yuan, Jingzhen, Odinokova, Irina V., Mareninova, Olga, Gukovskaya, Anna S., Pandol, Stephen J.
Gepubliceerd in 2010

Grp78 Heterozygosity Regulates Chaperone Balance in Exocrine Pancreas with Differential Response to Cerulein-Induced Acute Pancreatitis

door Ye, Risheng, Mareninova, Olga A., Barron, Ernesto, Wang, Miao, Hinton, David R., Pandol, Stephen J., Lee, Amy S.
Gepubliceerd in 2010

Genetic inhibition of protein kinase Cε attenuates necrosis in experimental pancreatitis

door Liu, Yannan, Yuan, Jingzhen, Tan, Tanya, Jia, Wenzhuo, Lugea, Aurelia, Mareninova, Olga, Waldron, Richard T., Pandol, Stephen J.
Gepubliceerd in 2014

Prosurvival Bcl-2 proteins stabilize pancreatic mitochondria and protect against necrosis in experimental pancreatitis

door Sung, Kai-Feng, Odinokova, Irina V., Mareninova, Olga A., Rakonczay, Zoltán, Hegyi, Péter, Pandol, Stephen J., Gukovsky, Ilya, Gukovskaya, Anna S.
Gepubliceerd in Exp Cell Res (2009)

Recent Insights Into the Pathogenic Mechanism of Pancreatitis: Role of Acinar Cell Organelle Disorders

door Gukovskaya, Anna S., Gorelick, Fred S., Groblewski, Guy E., Mareninova, Olga A., Lugea, Aurelia, Antonucci, Laura, Waldron, Richard T., Habtezion, Aida, Karin, Michael, Pandol, Stephen J., Gukovsky, Ilya
Gepubliceerd in Pancreas (2019)

Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis

door Mareninova, Olga A., Hermann, Kip, French, Samuel W., O’Konski, Mark S., Pandol, Stephen J., Webster, Paul, Erickson, Ann H., Katunuma, Nobuhiko, Gorelick, Fred S., Gukovsky, Ilya, Gukovskaya, Anna S.
Gepubliceerd in 2009

Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis

door Mareninova, Olga A., Hermann, Kip, French, Samuel W., O’Konski, Mark S., Pandol, Stephen J., Webster, Paul, Erickson, Ann H., Katunuma, Nobuhiko, Gorelick, Fred S., Gukovsky, Ilya, Gukovskaya, Anna S.
Gepubliceerd in 2013

Acute acinar pancreatitis blocks vesicle-associated membrane protein 8 (VAMP8)-dependent secretion, resulting in intracellular trypsin accumulation

door Messenger, Scott W., Jones, Elaina K., Holthaus, Conner L., Thomas, Diana D. H., Cooley, Michelle M., Byrne, Jennifer A., Mareninova, Olga A., Gukovskaya, Anna S., Groblewski, Guy E.
Gepubliceerd in J Biol Chem (2017)

Transgenic expression of GFP-LC3 perturbs autophagy in exocrine pancreas and acute pancreatitis responses in mice

door Mareninova, Olga A., Jia, Wenzhuo, Gretler, Sophie R., Holthaus, Conner L., Thomas, Diana D. H., Pimienta, Michael, Dillon, Dustin L., Gukovskaya, Anna S., Gukovsky, Ilya, Groblewski, Guy E.
Gepubliceerd in Autophagy (2020)

Roles of autophagy and metabolism in pancreatic cancer cell adaptation to environmental challenges

door Maertin, Sandrina, Elperin, Jason M., Lotshaw, Ethan, Sendler, Matthias, Speakman, Steven D., Takakura, Kazuki, Reicher, Benjamin M., Mareninova, Olga A., Grippo, Paul J., Mayerle, Julia, Lerch, Markus M., Gukovskaya, Anna S.
Gepubliceerd in Am J Physiol Gastrointest Liver Physiol (2017)

Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis

door Wang, Shaogui, Ni, Hong-Min, Chao, Xiaojuan, Wang, Hua, Bridges, Brian, Kumer, Sean, Schmitt, Timothy, Mareninova, Olga, Gukovskaya, Anna, De Lisle, Robert C., Ballabio, Andrea, Pacher, Pal, Ding, Wen-Xing
Gepubliceerd in Autophagy (2019)

Lysosome-Associated Membrane Proteins (LAMP) Maintain Pancreatic Acinar Cell Homeostasis: LAMP-2–Deficient Mice Develop Pancreatitis

door Mareninova, Olga A., Sendler, Matthias, Malla, Sudarshan Ravi, Yakubov, Iskandar, French, Samuel W., Tokhtaeva, Elmira, Vagin, Olga, Oorschot, Viola, Lüllmann-Rauch, Renate, Blanz, Judith, Dawson, David, Klumperman, Judith, Lerch, Markus M., Mayerle, Julia, Gukovsky, Ilya, Gukovskaya, Anna S.
Gepubliceerd in Cell Mol Gastroenterol Hepatol (2015)

Human Pancreatic Acinar Cells: Proteomic Characterization, Physiologic Responses, and Organellar Disorders in ex Vivo Pancreatitis

door Lugea, Aurelia, Waldron, Richard T., Mareninova, Olga A., Shalbueva, Natalia, Deng, Nan, Su, Hsin-Yuan, Thomas, Diane D., Jones, Elaina K., Messenger, Scott W., Yang, Jiayue, Hu, Cheng, Gukovsky, Ilya, Liu, Zhenqiu, Groblewski, Guy E., Gukovskaya, Anna S., Gorelick, Fred S., Pandol, Stephen J.
Gepubliceerd in Am J Pathol (2017)

Mitochondrial Dysfunction, Through Impaired Autophagy, Leads to Endoplasmic Reticulum Stress, Deregulated Lipid Metabolism, and Pancreatitis in Animal Models

door Biczo, Gyorgy, Vegh, Eszter T., Shalbueva, Natalia, Mareninova, Olga A., Elperin, Jason, Lotshaw, Ethan, Gretler, Sophie, Lugea, Aurelia, Malla, Sudarshan R., Dawson, David, Ruchala, Piotr, Whitelegge, Julian, French, Samuel W., Wen, Li, Husain, Sohail Z., Gorelick, Fred S., Hegyi, Peter, Rakonczay, Zoltan, Gukovsky, Ilya, Gukovskaya, Anna S.
Gepubliceerd in Gastroenterology (2017)

Dysregulation of mannose-6-phosphate–dependent cholesterol homeostasis in acinar cells mediates pancreatitis

door Mareninova, Olga A., Vegh, Eszter T., Shalbueva, Natalia, Wightman, Carli J.M., Dillon, Dustin L., Malla, Sudarshan, Xie, Yan, Takahashi, Toshimasa, Rakonczay, Zoltan, French, Samuel W., Gaisano, Herbert Y., Gorelick, Fred S., Pandol, Stephen J., Bensinger, Steven J., Davidson, Nicholas O., Dawson, David W., Gukovsky, Ilya, Gukovskaya, Anna S.
Gepubliceerd in J Clin Invest (2021)

Mechanism of mitochondrial permeability transition pore induction and damage in the pancreas: inhibition prevents acute pancreatitis by protecting production of ATP

door Mukherjee, Rajarshi, Mareninova, Olga A, Odinokova, Irina V, Huang, Wei, Murphy, John, Chvanov, Michael, Javed, Muhammad A, Wen, Li, Booth, David M, Cane, Matthew C, Awais, Muhammad, Gavillet, Bruno, Pruss, Rebecca M, Schaller, Sophie, Molkentin, Jeffery D, Tepikin, Alexei V, Petersen, Ole H, Pandol, Stephen J, Gukovsky, Ilya, Criddle, David N, Gukovskaya, Anna S, Sutton, Robert
Gepubliceerd in Gut (2016)