Transgenic expression of GFP-LC3 perturbs autophagy in exocrine pancreas and acute pancreatitis responses in mice

Pancreatitis is a common, sometimes fatal, disease of exocrine pancreas, initiated by damaged acinar cells. Recent studies implicate disordered macroautophagy/autophagy in pancreatitis pathogenesis. ATG8/LC3 protein is critical for autophagosome formation and a widely used marker of autophagic vacuo...

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Bibliografische gegevens
Gepubliceerd in:Autophagy
Hoofdauteurs: Mareninova, Olga A., Jia, Wenzhuo, Gretler, Sophie R., Holthaus, Conner L., Thomas, Diana D. H., Pimienta, Michael, Dillon, Dustin L., Gukovskaya, Anna S., Gukovsky, Ilya, Groblewski, Guy E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2020
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7595606/
https://ncbi.nlm.nih.gov/pubmed/31942816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1715047
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