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Prosurvival Bcl-2 proteins stabilize pancreatic mitochondria and protect against necrosis in experimental pancreatitis

Acinar cells in pancreatitis die through apoptosis and necrosis, the roles of which are different. The severity of experimental pancreatitis correlates directly with the extent of necrosis and inversely, with apoptosis. Apoptosis is mediated by the release of cytochrome c into the cytosol followed b...

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Detalhes bibliográficos
Publicado no:Exp Cell Res
Main Authors: Sung, Kai-Feng, Odinokova, Irina V., Mareninova, Olga A., Rakonczay, Zoltán, Hegyi, Péter, Pandol, Stephen J., Gukovsky, Ilya, Gukovskaya, Anna S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545253/
https://ncbi.nlm.nih.gov/pubmed/19331832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2009.01.009
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