Grp78 Heterozygosity Regulates Chaperone Balance in Exocrine Pancreas with Differential Response to Cerulein-Induced Acute Pancreatitis

The endoplasmic reticulum (ER) is abundant in the acinar cells of the exocrine pancreas. To test the role of ER homeostasis in acute pancreatitis, we manipulated GRP78 levels, a major ER chaperone, in mice. Grp78(+/+) and (+/−) littermates were fed either a regular diet (RD) or a high-fat diet. Acin...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Ye, Risheng, Mareninova, Olga A., Barron, Ernesto, Wang, Miao, Hinton, David R., Pandol, Stephen J., Lee, Amy S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Investigative Pathology 2010
विषय:
Regular Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993313/
https://ncbi.nlm.nih.gov/pubmed/20971738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100368
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