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Roles of autophagy and metabolism in pancreatic cancer cell adaptation to environmental challenges

Pancreatic ductal adenocarcinoma (PDAC) displays extensive and poorly vascularized desmoplastic stromal reaction, and therefore, pancreatic cancer (PaCa) cells are confronted with nutrient deprivation and hypoxia. Here, we investigate the roles of autophagy and metabolism in PaCa cell adaptation to...

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Bibliografiset tiedot
Julkaisussa:Am J Physiol Gastrointest Liver Physiol
Päätekijät: Maertin, Sandrina, Elperin, Jason M., Lotshaw, Ethan, Sendler, Matthias, Speakman, Steven D., Takakura, Kazuki, Reicher, Benjamin M., Mareninova, Olga A., Grippo, Paul J., Mayerle, Julia, Lerch, Markus M., Gukovskaya, Anna S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792215/
https://ncbi.nlm.nih.gov/pubmed/28705806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00138.2017
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