Analysis of N- and O-Glycosylation of Lysosomal Glycoproteins

Por Tokhtaeva, Elmira, Mareninova, Olga A., Gukovskaya, Anna S., Vagin, Olga
Publicado no Methods Mol Biol (2017)

Impaired Autophagy and Organellar Dysfunction in Pancreatitis

Por Gukovsky, Ilya, Pandol, Stephen J., Mareninova, Olga A., Shalbueva, Natalia, Jia, Wenzhuo, Gukovskaya, Anna S.
Publicado em 2012

Investigating the Pathobiology of Alcoholic Pancreatitis

Por Pandol, Stephen J., Lugea, Aurelia, Mareninova, Olga A., Smoot, Duane, Gorelick, Fred S., Gukovskaya, Anna S., Gukovsky, Ilya
Publicado em 2011

Effects of Oxidative Alcohol Metabolism on the Mitochondrial Permeability Transition Pore and Necrosis in a Mouse Model of Alcoholic Pancreatitis

Por SHALBUEVA, NATALIA, MARENINOVA, OLGA A., GERLOFF, ANDREAS, YUAN, JINGZHEN, WALDRON, RICHARD T., PANDOL, STEPHEN J., GUKOVSKAYA, ANNA S.
Publicado em 2012

Inflammatory cells regulate p53 and caspases in acute pancreatitis

Por Nakamura, Yuji, Do, Jae Hyuk, Yuan, Jingzhen, Odinokova, Irina V., Mareninova, Olga, Gukovskaya, Anna S., Pandol, Stephen J.
Publicado em 2010

Grp78 Heterozygosity Regulates Chaperone Balance in Exocrine Pancreas with Differential Response to Cerulein-Induced Acute Pancreatitis

Por Ye, Risheng, Mareninova, Olga A., Barron, Ernesto, Wang, Miao, Hinton, David R., Pandol, Stephen J., Lee, Amy S.
Publicado em 2010

Genetic inhibition of protein kinase Cε attenuates necrosis in experimental pancreatitis

Por Liu, Yannan, Yuan, Jingzhen, Tan, Tanya, Jia, Wenzhuo, Lugea, Aurelia, Mareninova, Olga, Waldron, Richard T., Pandol, Stephen J.
Publicado em 2014

Prosurvival Bcl-2 proteins stabilize pancreatic mitochondria and protect against necrosis in experimental pancreatitis

Por Sung, Kai-Feng, Odinokova, Irina V., Mareninova, Olga A., Rakonczay, Zoltán, Hegyi, Péter, Pandol, Stephen J., Gukovsky, Ilya, Gukovskaya, Anna S.
Publicado no Exp Cell Res (2009)

Recent Insights Into the Pathogenic Mechanism of Pancreatitis: Role of Acinar Cell Organelle Disorders

Por Gukovskaya, Anna S., Gorelick, Fred S., Groblewski, Guy E., Mareninova, Olga A., Lugea, Aurelia, Antonucci, Laura, Waldron, Richard T., Habtezion, Aida, Karin, Michael, Pandol, Stephen J., Gukovsky, Ilya
Publicado no Pancreas (2019)

Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis

Por Mareninova, Olga A., Hermann, Kip, French, Samuel W., O’Konski, Mark S., Pandol, Stephen J., Webster, Paul, Erickson, Ann H., Katunuma, Nobuhiko, Gorelick, Fred S., Gukovsky, Ilya, Gukovskaya, Anna S.
Publicado em 2009

Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis

Por Mareninova, Olga A., Hermann, Kip, French, Samuel W., O’Konski, Mark S., Pandol, Stephen J., Webster, Paul, Erickson, Ann H., Katunuma, Nobuhiko, Gorelick, Fred S., Gukovsky, Ilya, Gukovskaya, Anna S.
Publicado em 2013

Acute acinar pancreatitis blocks vesicle-associated membrane protein 8 (VAMP8)-dependent secretion, resulting in intracellular trypsin accumulation

Por Messenger, Scott W., Jones, Elaina K., Holthaus, Conner L., Thomas, Diana D. H., Cooley, Michelle M., Byrne, Jennifer A., Mareninova, Olga A., Gukovskaya, Anna S., Groblewski, Guy E.
Publicado no J Biol Chem (2017)

Transgenic expression of GFP-LC3 perturbs autophagy in exocrine pancreas and acute pancreatitis responses in mice

Por Mareninova, Olga A., Jia, Wenzhuo, Gretler, Sophie R., Holthaus, Conner L., Thomas, Diana D. H., Pimienta, Michael, Dillon, Dustin L., Gukovskaya, Anna S., Gukovsky, Ilya, Groblewski, Guy E.
Publicado no Autophagy (2020)

Roles of autophagy and metabolism in pancreatic cancer cell adaptation to environmental challenges

Por Maertin, Sandrina, Elperin, Jason M., Lotshaw, Ethan, Sendler, Matthias, Speakman, Steven D., Takakura, Kazuki, Reicher, Benjamin M., Mareninova, Olga A., Grippo, Paul J., Mayerle, Julia, Lerch, Markus M., Gukovskaya, Anna S.
Publicado no Am J Physiol Gastrointest Liver Physiol (2017)

Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis

Por Wang, Shaogui, Ni, Hong-Min, Chao, Xiaojuan, Wang, Hua, Bridges, Brian, Kumer, Sean, Schmitt, Timothy, Mareninova, Olga, Gukovskaya, Anna, De Lisle, Robert C., Ballabio, Andrea, Pacher, Pal, Ding, Wen-Xing
Publicado no Autophagy (2019)

Lysosome-Associated Membrane Proteins (LAMP) Maintain Pancreatic Acinar Cell Homeostasis: LAMP-2–Deficient Mice Develop Pancreatitis

Por Mareninova, Olga A., Sendler, Matthias, Malla, Sudarshan Ravi, Yakubov, Iskandar, French, Samuel W., Tokhtaeva, Elmira, Vagin, Olga, Oorschot, Viola, Lüllmann-Rauch, Renate, Blanz, Judith, Dawson, David, Klumperman, Judith, Lerch, Markus M., Mayerle, Julia, Gukovsky, Ilya, Gukovskaya, Anna S.
Publicado no Cell Mol Gastroenterol Hepatol (2015)

Human Pancreatic Acinar Cells: Proteomic Characterization, Physiologic Responses, and Organellar Disorders in ex Vivo Pancreatitis

Por Lugea, Aurelia, Waldron, Richard T., Mareninova, Olga A., Shalbueva, Natalia, Deng, Nan, Su, Hsin-Yuan, Thomas, Diane D., Jones, Elaina K., Messenger, Scott W., Yang, Jiayue, Hu, Cheng, Gukovsky, Ilya, Liu, Zhenqiu, Groblewski, Guy E., Gukovskaya, Anna S., Gorelick, Fred S., Pandol, Stephen J.
Publicado no Am J Pathol (2017)

Mitochondrial Dysfunction, Through Impaired Autophagy, Leads to Endoplasmic Reticulum Stress, Deregulated Lipid Metabolism, and Pancreatitis in Animal Models

Por Biczo, Gyorgy, Vegh, Eszter T., Shalbueva, Natalia, Mareninova, Olga A., Elperin, Jason, Lotshaw, Ethan, Gretler, Sophie, Lugea, Aurelia, Malla, Sudarshan R., Dawson, David, Ruchala, Piotr, Whitelegge, Julian, French, Samuel W., Wen, Li, Husain, Sohail Z., Gorelick, Fred S., Hegyi, Peter, Rakonczay, Zoltan, Gukovsky, Ilya, Gukovskaya, Anna S.
Publicado no Gastroenterology (2017)

Mechanism of mitochondrial permeability transition pore induction and damage in the pancreas: inhibition prevents acute pancreatitis by protecting production of ATP

Por Mukherjee, Rajarshi, Mareninova, Olga A, Odinokova, Irina V, Huang, Wei, Murphy, John, Chvanov, Michael, Javed, Muhammad A, Wen, Li, Booth, David M, Cane, Matthew C, Awais, Muhammad, Gavillet, Bruno, Pruss, Rebecca M, Schaller, Sophie, Molkentin, Jeffery D, Tepikin, Alexei V, Petersen, Ole H, Pandol, Stephen J, Gukovsky, Ilya, Criddle, David N, Gukovskaya, Anna S, Sutton, Robert
Publicado no Gut (2016)