Increasing the Power to Detect Causal Associations by Combining Genotypic and Expression Data in Segregating Populations

著者: Zhu, Jun, Wiener, Matthew C, Zhang, Chunsheng, Fridman, Arthur, Minch, Eric, Lum, Pek Y, Sachs, Jeffrey R, Schadt, Eric E
出版事項 2007

Topological data analysis of Escherichia coli O157:H7 and non-O157 survival in soils

著者: Ibekwe, Abasiofiok M., Ma, Jincai, Crowley, David E., Yang, Ching-Hong, Johnson, Alexis M., Petrossian, Tanya C., Lum, Pek Y.
出版事項 2014

Development of the Digital Arthritis Index, a Novel Metric to Measure Disease Parameters in a Rat Model of Rheumatoid Arthritis

著者: Lim, Maria A., Louie, Brenton, Ford, Daniel, Heath, Kyle, Cha, Paulyn, Betts-Lacroix, Joe, Lum, Pek Yee, Robertson, Timothy L., Schaevitz, Laura
出版年 Front Pharmacol (2017)

An eQTL biological data visualization challenge and approaches from the visualization community

著者: Bartlett, Christopher W, Yeon Cheong, Soo, Hou, Liping, Paquette, Jesse, Yee Lum, Pek, Jäger, Günter, Battke, Florian, Vehlow, Corinna, Heinrich, Julian, Nieselt, Kay, Sakai, Ryo, Aerts, Jan, Ray, William C
出版事項 2012

Acridine Derivatives as Inhibitors of the IRE1α-XBP1 Pathway Cytotoxic to Human Multiple Myeloma

著者: Jiang, Dadi, Tam, Arvin, Alagappan, Muthuraman, Hay, Michael P., Gupta, Aparna, Kozak, Margaret, Solow-Cordero, David E., Lum, Pek Y, Denko, Nicholas, Giaccia, Amato J., Le, Quynh-Thu, Niwa, Maho, Koong, Albert C.
出版年 Mol Cancer Ther (2016)

Innate and adaptive T cells in asthmatic patients: Relationship to severity and disease mechanisms

著者: Hinks, Timothy S.C., Zhou, Xiaoying, Staples, Karl J., Dimitrov, Borislav D., Manta, Alexander, Petrossian, Tanya, Lum, Pek Y., Smith, Caroline G., Ward, Jon A., Howarth, Peter H., Walls, Andrew F., Gadola, Stephan D., Djukanović, Ratko
出版年 J Allergy Clin Immunol (2015)

Diurnal variation of the human adipose transcriptome and the link to metabolic disease

著者: Loboda, Andrey, Kraft, Walter K, Fine, Bernard, Joseph, Jeffrey, Nebozhyn, Michael, Zhang, Chunsheng, He, Yudong, Yang, Xia, Wright, Christopher, Morris, Mark, Chalikonda, Ira, Ferguson, Mark, Emilsson, Valur, Leonardson, Amy, Lamb, John, Dai, Hongyue, Schadt, Eric, Greenberg, Howard E, Lum, Pek Yee
出版事項 2009

Common body mass index-associated variants confer risk of extreme obesity

著者: Cotsapas, Chris, Speliotes, Elizabeth K., Hatoum, Ida J., Greenawalt, Danielle M., Dobrin, Radu, Lum, Pek Y., Suver, Christine, Chudin, Eugene, Kemp, Daniel, Reitman, Marc, Voight, Benjamin F., Neale, Benjamin M., Schadt, Eric E., Hirschhorn, Joel N., Kaplan, Lee M., Daly, Mark J.
出版事項 2009

Common body mass index-associated variants confer risk of extreme obesity

著者: Cotsapas, Chris, Speliotes, Elizabeth K., Hatoum, Ida J., Greenawalt, Danielle M., Dobrin, Radu, Lum, Pek Y., Suver, Christine, Chudin, Eugene, Kemp, Daniel, Reitman, Marc, Voight, Benjamin F., Neale, Benjamin M., Schadt, Eric E., Hirschhorn, Joel N., Kaplan, Lee M., Daly, Mark J.
出版事項 2010

A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort

著者: Greenawalt, Danielle M., Dobrin, Radu, Chudin, Eugene, Hatoum, Ida J., Suver, Christine, Beaulaurier, John, Zhang, Bin, Castro, Victor, Zhu, Jun, Sieberts, Solveig K., Wang, Susanna, Molony, Cliona, Heymsfield, Steven B., Kemp, Daniel M., Reitman, Marc L., Lum, Pek Yee, Schadt, Eric E., Kaplan, Lee M.
出版事項 2011

Integrative Analysis of a Cross-Loci Regulation Network Identifies App as a Gene Regulating Insulin Secretion from Pancreatic Islets

著者: Tu, Zhidong, Keller, Mark P., Zhang, Chunsheng, Rabaglia, Mary E., Greenawalt, Danielle M., Yang, Xia, Wang, I-Ming, Dai, Hongyue, Bruss, Matthew D., Lum, Pek Y., Zhou, Yun-Ping, Kemp, Daniel M., Kendziorski, Christina, Yandell, Brian S., Attie, Alan D., Schadt, Eric E., Zhu, Jun
出版事項 2012

Topological data analysis for discovery in preclinical spinal cord injury and traumatic brain injury

著者: Nielson, Jessica L., Paquette, Jesse, Liu, Aiwen W., Guandique, Cristian F., Tovar, C. Amy, Inoue, Tomoo, Irvine, Karen-Amanda, Gensel, John C., Kloke, Jennifer, Petrossian, Tanya C., Lum, Pek Y., Carlsson, Gunnar E., Manley, Geoffrey T., Young, Wise, Beattie, Michael S., Bresnahan, Jacqueline C., Ferguson, Adam R.
出版年 Nat Commun (2015)

Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver

著者: Yang, Xia, Zhang, Bin, Molony, Cliona, Chudin, Eugene, Hao, Ke, Zhu, Jun, Gaedigk, Andrea, Suver, Christine, Zhong, Hua, Leeder, J. Steven, Guengerich, F. Peter, Strom, Stephen C., Schuetz, Erin, Rushmore, Thomas H., Ulrich, Roger G., Slatter, J. Greg, Schadt, Eric E., Kasarskis, Andrew, Lum, Pek Yee
出版事項 2010

An integrative genomics approach to infer causal associations between gene expression and disease

著者: Schadt, Eric E, Lamb, John, Yang, Xia, Zhu, Jun, Edwards, Steve, GuhaThakurta, Debraj, Sieberts, Solveig K, Monks, Stephanie, Reitman, Marc, Zhang, Chunsheng, Lum, Pek Yee, Leonardson, Amy, Thieringer, Rolf, Metzger, Joseph M, Yang, Liming, Castle, John, Zhu, Haoyuan, Kash, Shera F, Drake, Thomas A, Sachs, Alan, Lusis, Aldons J
出版事項 2005

Uncovering precision phenotype-biomarker associations in traumatic brain injury using topological data analysis

著者: Nielson, Jessica L., Cooper, Shelly R., Yue, John K., Sorani, Marco D., Inoue, Tomoo, Yuh, Esther L., Mukherjee, Pratik, Petrossian, Tanya C., Paquette, Jesse, Lum, Pek Y., Carlsson, Gunnar E., Vassar, Mary J., Lingsma, Hester F., Gordon, Wayne A., Valadka, Alex B., Okonkwo, David O., Manley, Geoffrey T., Ferguson, Adam R.
出版年 PLoS One (2017)

Variations in DNA elucidate molecular networks that cause disease

著者: Chen, Yanqing, Zhu, Jun, Lum, Pek Yee, Yang, Xia, Pinto, Shirly, MacNeil, Douglas J., Zhang, Chunsheng, Lamb, John, Edwards, Stephen, Sieberts, Solveig K., Leonardson, Amy, Castellini, Lawrence W., Wang, Susanna, Champy, Marie-France, Zhang, Bin, Emilsson, Valur, Doss, Sudheer, Ghazalpour, Anatole, Horvath, Steve, Drake, Thomas A., Lusis, Aldons J., Schadt, Eric E.
出版事項 2008

Identification and validation of genes affecting aortic lesions in mice

著者: Yang, Xia, Peterson, Larry, Thieringer, Rolf, Deignan, Joshua L., Wang, Xuping, Zhu, Jun, Wang, Susanna, Zhong, Hua, Stepaniants, Serguei, Beaulaurier, John, Wang, I-Ming, Rosa, Ray, Cumiskey, Anne-Marie, Luo, Jane Ming-Juan, Luo, Qi, Shah, Kashmira, Xiao, Jianying, Nickle, David, Plump, Andrew, Schadt, Eric E., Lusis, Aldons J., Lum, Pek Yee
出版事項 2010

Liver and Adipose Expression Associated SNPs Are Enriched for Association to Type 2 Diabetes

著者: Zhong, Hua, Beaulaurier, John, Lum, Pek Yee, Molony, Cliona, Yang, Xia, MacNeil, Douglas J., Weingarth, Drew T., Zhang, Bin, Greenawalt, Danielle, Dobrin, Radu, Hao, Ke, Woo, Sangsoon, Fabre-Suver, Christine, Qian, Su, Tota, Michael R., Keller, Mark P., Kendziorski, Christina M., Yandell, Brian S., Castro, Victor, Attie, Alan D., Kaplan, Lee M., Schadt, Eric E.
出版事項 2010

Obesity and genetics regulate microRNAs in islets, liver and adipose of diabetic mice

著者: Zhao, Enpeng, Keller, Mark P., Rabaglia, Mary E., Oler, Angie T., Stapleton, Donnie S., Schueler, Kathryn L., Neto, Elias Chaibub, Moon, Jee Young, Wang, Ping, Wang, I-Ming, Lum, Pek, Ivanovska, Irena, Greenawalt, Danielle, Tsang, John, Choi, YounJeong, Kleinhanz, Robert, Shang, Jin, Zhou, Yun-Ping, Howard, Andrew D., Zhang, Bei B., Kendziorski, Christina, Thornberry, Nancy A., Yandell, Brian S., Schadt, Eric E., Attie, Alan D.
出版事項 2009

Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers

著者: Wang, I-Ming, Zhang, Bin, Yang, Xia, Zhu, Jun, Stepaniants, Serguei, Zhang, Chunsheng, Meng, Qingying, Peters, Mette, He, Yudong, Ni, Chester, Slipetz, Deborah, Crackower, Michael A, Houshyar, Hani, Tan, Christopher M, Asante-Appiah, Ernest, O'Neill, Gary, Jane Luo, Mingjuan, Thieringer, Rolf, Yuan, Jeffrey, Chiu, Chi-Sung, Yee Lum, Pek, Lamb, John, Boie, Yves, Wilkinson, Hilary A, Schadt, Eric E, Dai, Hongyue, Roberts, Christopher
出版事項 2012