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Variations in DNA elucidate molecular networks that cause disease

Identifying variations in DNA that increase susceptibility to disease is one of the primary aims of genetic studies using a forward genetics approach. However, identification of disease-susceptibility genes by means of such studies provides limited functional information on how genes lead to disease...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chen, Yanqing, Zhu, Jun, Lum, Pek Yee, Yang, Xia, Pinto, Shirly, MacNeil, Douglas J., Zhang, Chunsheng, Lamb, John, Edwards, Stephen, Sieberts, Solveig K., Leonardson, Amy, Castellini, Lawrence W., Wang, Susanna, Champy, Marie-France, Zhang, Bin, Emilsson, Valur, Doss, Sudheer, Ghazalpour, Anatole, Horvath, Steve, Drake, Thomas A., Lusis, Aldons J., Schadt, Eric E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841398/
https://ncbi.nlm.nih.gov/pubmed/18344982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06757
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