Common body mass index-associated variants confer risk of extreme obesity

To investigate the genetic architecture of severe obesity, we performed a genome-wide association study of 775 cases and 3197 unascertained controls at ∼550 000 markers across the autosomal genome. We found convincing association to the previously described locus including the FTO gene. We also foun...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cotsapas, Chris, Speliotes, Elizabeth K., Hatoum, Ida J., Greenawalt, Danielle M., Dobrin, Radu, Lum, Pek Y., Suver, Christine, Chudin, Eugene, Kemp, Daniel, Reitman, Marc, Voight, Benjamin F., Neale, Benjamin M., Schadt, Eric E., Hirschhorn, Joel N., Kaplan, Lee M., Daly, Mark J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2009
Gaiak:
Association Studies Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729668/
https://ncbi.nlm.nih.gov/pubmed/19553259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp292
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