The structure of apo protein-tyrosine phosphatase 1B C215S mutant: More than just an S → O change

par Scapin, Giovanna, Patel, Sangita, Patel, Vira, Kennedy, Brian, Asante-Appiah, Ernest
Publié 2001

Unraveling the structural basis of grazoprevir potency against clinically relevant substitutions in hepatitis C virus NS3/4A protease from genotype 1a

par Guo, Zhuyan, Black, Stuart, Hu, Yuan, McMonagle, Patricia, Ingravallo, Paul, Chase, Robert, Curry, Stephanie, Asante-Appiah, Ernest
Publié dans J Biol Chem (2017)

Antiviral Activity and Resistance Analysis of NS3/4A Protease Inhibitor Grazoprevir and NS5A Inhibitor Elbasvir in Hepatitis C Virus GT4 Replicons

par Asante-Appiah, Ernest, Curry, Stephanie, McMonagle, Patricia, Ingravallo, Paul, Chase, Robert, Nickle, David, Qiu, Ping, Howe, Anita, Lahser, Frederick C.
Publié dans Antimicrob Agents Chemother (2017)

Interplay of Amino Acid Residues at Positions 28 and 31 in NS5A Defines Resistance Pathways in Hepatitis C Virus Genotype 2

par Asante-Appiah, Ernest, Ingravallo, Paul, McMonagle, Patricia, Bystol, Karin, Xia, Ellen, Curry, Stephanie, Qiu, Ping, Black, Stuart, Chase, Robert, Liu, Rong, Lahser, Fred
Publié dans Antimicrob Agents Chemother (2019)

Review of Doravirine Resistance Patterns Identified in Participants During Clinical Development

par Martin, Elizabeth Anne, Lai, Ming-Tain, Ngo, Winnie, Feng, Meizhen, Graham, Donald, Hazuda, Daria J., Kumar, Sushma, Hwang, Carey, Sklar, Peter, Asante-Appiah, Ernest
Publié dans J Acquir Immune Defic Syndr (2020)

Kinetic Analyses Reveal Potent and Early Blockade of Hepatitis C Virus Assembly by NS5A Inhibitors

par McGivern, David R., Masaki, Takahiro, Williford, Sara, Ingravallo, Paul, Feng, Zongdi, Lahser, Frederick, Asante-Appiah, Ernest, Neddermann, Petra, Francesco, Raffaele De, Howe, Anita Y., Lemon, Stanley M.
Publié 2014

The Combination of Grazoprevir, a Hepatitis C Virus (HCV) NS3/4A Protease Inhibitor, and Elbasvir, an HCV NS5A Inhibitor, Demonstrates a High Genetic Barrier to Resistance in HCV G...

par Lahser, Frederick C., Bystol, Karin, Curry, Stephanie, McMonagle, Patricia, Xia, Ellen, Ingravallo, Paul, Chase, Robert, Liu, Rong, Black, Todd, Hazuda, Daria, Howe, Anita Y. M., Asante-Appiah, Ernest
Publié dans Antimicrob Agents Chemother (2016)

Evolutionary pathways to NS5A inhibitor resistance in genotype 1 hepatitis C virus

par Zhou, Shuntai, Williford, Sara E., McGivern, David R., Burch, Christina L., Hu, Fengyu, Benzine, Tiffany, Ingravallo, Paul, Asante-Appiah, Ernest, Howe, Anita Y.M., Swanstrom, Ronald, Lemon, Stanley M.
Publié dans Antiviral Res (2018)

In Vitro Antiviral Profile of Ruzasvir, a Potent and Pangenotype Inhibitor of Hepatitis C Virus NS5A

par Asante-Appiah, Ernest, Liu, Rong, Curry, Stephanie, McMonagle, Patricia, Agrawal, Sony, Carr, Donna, Rokosz, Laura, Lahser, Frederick, Bystol, Karin, Chase, Robert, Black, Stuart, Ferrari, Eric, Ingravallo, Paul, Tong, Ling, Yu, Wensheng, Kozlowski, Joseph
Publié dans Antimicrob Agents Chemother (2018)

In Vitro Characterization of MK-1439, a Novel HIV-1 Nonnucleoside Reverse Transcriptase Inhibitor

par Lai, Ming-Tain, Feng, Meizhen, Falgueyret, Jean-Pierre, Tawa, Paul, Witmer, Marc, DiStefano, Daniel, Li, Yuan, Burch, Jason, Sachs, Nancy, Lu, Meiqing, Cauchon, Elizabeth, Campeau, Louis-Charles, Grobler, Jay, Yan, Youwei, Ducharme, Yves, Côté, Bernard, Asante-Appiah, Ernest, Hazuda, Daria J., Miller, Michael D.
Publié 2014

Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers

par Wang, I-Ming, Zhang, Bin, Yang, Xia, Zhu, Jun, Stepaniants, Serguei, Zhang, Chunsheng, Meng, Qingying, Peters, Mette, He, Yudong, Ni, Chester, Slipetz, Deborah, Crackower, Michael A, Houshyar, Hani, Tan, Christopher M, Asante-Appiah, Ernest, O'Neill, Gary, Jane Luo, Mingjuan, Thieringer, Rolf, Yuan, Jeffrey, Chiu, Chi-Sung, Yee Lum, Pek, Lamb, John, Boie, Yves, Wilkinson, Hilary A, Schadt, Eric E, Dai, Hongyue, Roberts, Christopher
Publié 2012

Efficacy and safety of elbasvir/grazoprevir in treatment‐naive Chinese adults with hepatitis C virus infection: A randomized trial

par Wei, Lai, Jia, Ji Dong, Duan, Zhong Ping, Wang, Fu Sheng, Niu, Jun Qi, Xie, Wen, Huang, Wen Xiang, Zhang, Ming Xiang, Huang, Yan, Wang, Mao Rong, Wu, Shan Ming, Zhao, Ying Ren, Jia, Zhan Sheng, Zhao, Xu Min, Mu, Sheng Mei, Liang, Li Wen, Wang, Zaiqi, Puenpatom, Amy, Hwang, Peggy, Robertson, Michael N., Ingravallo, Paul, Asante‐Appiah, Ernest, Wei, Bo, Evans, Barbara, Hanna, George J., Talwani, Rohit
Publié dans JGH Open (2020)