Obesity and genetics regulate microRNAs in islets, liver and adipose of diabetic mice

Type 2 diabetes results from severe insulin resistance coupled with a failure of β-cells to compensate by secreting sufficient insulin. Multiple genetic loci are involved in the development of diabetes, although the effect of each gene on diabetes susceptibility is thought to be small. MicroRNAs (mi...

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Main Authors: Zhao, Enpeng, Keller, Mark P., Rabaglia, Mary E., Oler, Angie T., Stapleton, Donnie S., Schueler, Kathryn L., Neto, Elias Chaibub, Moon, Jee Young, Wang, Ping, Wang, I-Ming, Lum, Pek, Ivanovska, Irena, Greenawalt, Danielle, Tsang, John, Choi, YounJeong, Kleinhanz, Robert, Shang, Jin, Zhou, Yun-Ping, Howard, Andrew D., Zhang, Bei B., Kendziorski, Christina, Thornberry, Nancy A., Yandell, Brian S., Schadt, Eric E., Attie, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879069/
https://ncbi.nlm.nih.gov/pubmed/19727952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-009-9217-2
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