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Genetic Drivers of Pancreatic Islet Function

The majority of gene loci that have been associated with type 2 diabetes play a role in pancreatic islet function. To evaluate the role of islet gene expression in the etiology of diabetes, we sensitized a genetically diverse mouse population with a Western diet high in fat (45% kcal) and sucrose (3...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Keller, Mark P., Gatti, Daniel M., Schueler, Kathryn L., Rabaglia, Mary E., Stapleton, Donnie S., Simecek, Petr, Vincent, Matthew, Allen, Sadie, Broman, Aimee Teo, Bacher, Rhonda, Kendziorski, Christina, Broman, Karl W., Yandell, Brian S., Churchill, Gary A., Attie, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937189/
https://ncbi.nlm.nih.gov/pubmed/29567659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.300864
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