Genetic Drivers of Pancreatic Islet Function

The majority of gene loci that have been associated with type 2 diabetes play a role in pancreatic islet function. To evaluate the role of islet gene expression in the etiology of diabetes, we sensitized a genetically diverse mouse population with a Western diet high in fat (45% kcal) and sucrose (3...

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Publicado en:Genetics
Autores principales: Keller, Mark P., Gatti, Daniel M., Schueler, Kathryn L., Rabaglia, Mary E., Stapleton, Donnie S., Simecek, Petr, Vincent, Matthew, Allen, Sadie, Broman, Aimee Teo, Bacher, Rhonda, Kendziorski, Christina, Broman, Karl W., Yandell, Brian S., Churchill, Gary A., Attie, Alan D.
Formato: Artigo
Lenguaje:Inglês
Publicado: Genetics Society of America 2018
Materias:
Investigations
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937189/
https://ncbi.nlm.nih.gov/pubmed/29567659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.300864
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