Gene loci associated with insulin secretion in islets from nondiabetic mice

Genetic susceptibility to type 2 diabetes is primarily due to β cell dysfunction. However, a genetic study to directly interrogate β cell function ex vivo has never been previously performed. We isolated 233,447 islets from 483 Diversity Outbred (DO) mice maintained on a Western-style diet, and meas...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Keller, Mark P., Rabaglia, Mary E., Schueler, Kathryn L., Stapleton, Donnie S., Gatti, Daniel M., Vincent, Matthew, Mitok, Kelly A., Wang, Ziyue, Ishimura, Takanao, Simonett, Shane P., Emfinger, Christopher H., Das, Rahul, Beck, Tim, Kendziorski, Christina, Broman, Karl W., Yandell, Brian S., Churchill, Gary A., Attie, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763251/
https://ncbi.nlm.nih.gov/pubmed/31343992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI129143
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados