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Islet proteomics reveals genetic variation in dopamine production resulting in altered insulin secretion

The mouse is a critical model in diabetes research, but most research in mice has been limited to a small number of mouse strains and limited genetic variation. Using the eight founder strains and both sexes of the Collaborative Cross (C57BL/6J (B6), A/J, 129S1/SvImJ (129), NOD/ShiLtJ (NOD), NZO/HIL...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Mitok, Kelly A., Freiberger, Elyse C., Schueler, Kathryn L., Rabaglia, Mary E., Stapleton, Donald S., Kwiecien, Nicholas W., Malec, Paige A., Hebert, Alexander S., Broman, Aimee T., Kennedy, Robert T., Keller, Mark P., Coon, Joshua J., Attie, Alan D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912463/
https://ncbi.nlm.nih.gov/pubmed/29496998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001102
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