Islet proteomics reveals genetic variation in dopamine production resulting in altered insulin secretion

The mouse is a critical model in diabetes research, but most research in mice has been limited to a small number of mouse strains and limited genetic variation. Using the eight founder strains and both sexes of the Collaborative Cross (C57BL/6J (B6), A/J, 129S1/SvImJ (129), NOD/ShiLtJ (NOD), NZO/HIL...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Mitok, Kelly A., Freiberger, Elyse C., Schueler, Kathryn L., Rabaglia, Mary E., Stapleton, Donald S., Kwiecien, Nicholas W., Malec, Paige A., Hebert, Alexander S., Broman, Aimee T., Kennedy, Robert T., Keller, Mark P., Coon, Joshua J., Attie, Alan D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2018
Schlagworte:
Genomics and Proteomics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912463/
https://ncbi.nlm.nih.gov/pubmed/29496998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001102
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