Islet proteomics reveals genetic variation in dopamine production resulting in altered insulin secretion

The mouse is a critical model in diabetes research, but most research in mice has been limited to a small number of mouse strains and limited genetic variation. Using the eight founder strains and both sexes of the Collaborative Cross (C57BL/6J (B6), A/J, 129S1/SvImJ (129), NOD/ShiLtJ (NOD), NZO/HIL...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Mitok, Kelly A., Freiberger, Elyse C., Schueler, Kathryn L., Rabaglia, Mary E., Stapleton, Donald S., Kwiecien, Nicholas W., Malec, Paige A., Hebert, Alexander S., Broman, Aimee T., Kennedy, Robert T., Keller, Mark P., Coon, Joshua J., Attie, Alan D.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2018
Subjects:
Genomics and Proteomics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912463/
https://ncbi.nlm.nih.gov/pubmed/29496998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001102
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