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Islet proteomics reveals genetic variation in dopamine production resulting in altered insulin secretion

The mouse is a critical model in diabetes research, but most research in mice has been limited to a small number of mouse strains and limited genetic variation. Using the eight founder strains and both sexes of the Collaborative Cross (C57BL/6J (B6), A/J, 129S1/SvImJ (129), NOD/ShiLtJ (NOD), NZO/HIL...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Mitok, Kelly A., Freiberger, Elyse C., Schueler, Kathryn L., Rabaglia, Mary E., Stapleton, Donald S., Kwiecien, Nicholas W., Malec, Paige A., Hebert, Alexander S., Broman, Aimee T., Kennedy, Robert T., Keller, Mark P., Coon, Joshua J., Attie, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912463/
https://ncbi.nlm.nih.gov/pubmed/29496998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001102
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