Identification of the Bile Acid Transporter Slco1a6 as a Candidate Gene That Broadly Affects Gene Expression in Mouse Pancreatic Islets

We surveyed gene expression in six tissues in an F(2) intercross between mouse strains C57BL/6J (abbreviated B6) and BTBR T(+) tf/J (abbreviated BTBR) made genetically obese with the Leptin(ob) mutation. We identified a number of expression quantitative trait loci (eQTL) affecting the expression of...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Tian, Jianan, Keller, Mark P., Oler, Angie T., Rabaglia, Mary E., Schueler, Kathryn L., Stapleton, Donald S., Broman, Aimee Teo, Zhao, Wen, Kendziorski, Christina, Yandell, Brian S., Hagenbuch, Bruno, Broman, Karl W., Attie, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2015
Assuntos:
Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649649/
https://ncbi.nlm.nih.gov/pubmed/26385979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.179432
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