Identification of the Bile Acid Transporter Slco1a6 as a Candidate Gene That Broadly Affects Gene Expression in Mouse Pancreatic Islets

We surveyed gene expression in six tissues in an F(2) intercross between mouse strains C57BL/6J (abbreviated B6) and BTBR T(+) tf/J (abbreviated BTBR) made genetically obese with the Leptin(ob) mutation. We identified a number of expression quantitative trait loci (eQTL) affecting the expression of...

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Gepubliceerd in:Genetics
Hoofdauteurs: Tian, Jianan, Keller, Mark P., Oler, Angie T., Rabaglia, Mary E., Schueler, Kathryn L., Stapleton, Donald S., Broman, Aimee Teo, Zhao, Wen, Kendziorski, Christina, Yandell, Brian S., Hagenbuch, Bruno, Broman, Karl W., Attie, Alan D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Genetics Society of America 2015
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Investigations
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649649/
https://ncbi.nlm.nih.gov/pubmed/26385979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.179432
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