Identification and Correction of Sample Mix-Ups in Expression Genetic Data: A Case Study

In a mouse intercross with more than 500 animals and genome-wide gene expression data on six tissues, we identified a high proportion (18%) of sample mix-ups in the genotype data. Local expression quantitative trait loci (eQTL; genetic loci influencing gene expression) with extremely large effect we...

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Bibliografiske detaljer
Udgivet i:G3 (Bethesda)
Main Authors: Broman, Karl W., Keller, Mark P., Broman, Aimee Teo, Kendziorski, Christina, Yandell, Brian S., Sen, Śaunak, Attie, Alan D.
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2015
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Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592999/
https://ncbi.nlm.nih.gov/pubmed/26290572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.115.019778
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