Obesity and genetics regulate microRNAs in islets, liver and adipose of diabetic mice

Type 2 diabetes results from severe insulin resistance coupled with a failure of β-cells to compensate by secreting sufficient insulin. Multiple genetic loci are involved in the development of diabetes, although the effect of each gene on diabetes susceptibility is thought to be small. MicroRNAs (mi...

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Main Authors: Zhao, Enpeng, Keller, Mark P., Rabaglia, Mary E., Oler, Angie T., Stapleton, Donnie S., Schueler, Kathryn L., Neto, Elias Chaibub, Moon, Jee Young, Wang, Ping, Wang, I-Ming, Lum, Pek, Ivanovska, Irena, Greenawalt, Danielle, Tsang, John, Choi, YounJeong, Kleinhanz, Robert, Shang, Jin, Zhou, Yun-Ping, Howard, Andrew D., Zhang, Bei B., Kendziorski, Christina, Thornberry, Nancy A., Yandell, Brian S., Schadt, Eric E., Attie, Alan D.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879069/
https://ncbi.nlm.nih.gov/pubmed/19727952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-009-9217-2
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