Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver

Liver cytochrome P450s (P450s) play critical roles in drug metabolism, toxicology, and metabolic processes. Despite rapid progress in the understanding of these enzymes, a systematic investigation of the full spectrum of functionality of individual P450s, the interrelationship or networks connecting...

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Detalhes bibliográficos
Main Authors: Yang, Xia, Zhang, Bin, Molony, Cliona, Chudin, Eugene, Hao, Ke, Zhu, Jun, Gaedigk, Andrea, Suver, Christine, Zhong, Hua, Leeder, J. Steven, Guengerich, F. Peter, Strom, Stephen C., Schuetz, Erin, Rushmore, Thomas H., Ulrich, Roger G., Slatter, J. Greg, Schadt, Eric E., Kasarskis, Andrew, Lum, Pek Yee
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909567/
https://ncbi.nlm.nih.gov/pubmed/20538623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.103341.109
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