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Mechanisms of Cytochrome P450-Catalyzed Oxidations

Enzymes are complex biological catalysts and are critical to life. Most oxidations of chemicals are catalyzed by cytochrome P450 (P450, CYP) enzymes, which generally utilize mixed-function oxidase stoichiometry, utilizing pyridine nucleotides as electron donors: NAD(P)H + O(2) + R → NAD(P)(+) + RO +...

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Bibliografische gegevens
Gepubliceerd in:ACS Catal
Hoofdauteur: Guengerich, F. Peter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6519473/
https://ncbi.nlm.nih.gov/pubmed/31105987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.8b03401
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