A Search History-Driven Offspring Generation Method for the Real-Coded Genetic Algorithm

od Nakane, Takumi, Lu, Xuequan, Zhang, Chao
Wydane w Comput Intell Neurosci (2020)

Mechanism-based inhibitors of MenE, an acyl-CoA synthetase involved in bacterial menaquinone biosynthesis

od Lu, Xuequan, Zhang, Huaning, Tonge, Peter J., Tan, Derek S.
Wydane 2008

Active site remodeling accompanies thioester bond formation in the SUMO E1

od Olsen, Shaun K., Capili, Allan D., Lu, Xuequan, Tan, Derek S., Lima, Christopher D.
Wydane 2010

Ceramide Synthesis Is Modulated by the Sphingosine Analog FTY720 via a Mixture of Uncompetitive and Noncompetitive Inhibition in an Acyl-CoA Chain Length-de pend ent Manner

od Lahiri, Sujoy, Park, Hyejung, Laviad, Elad L., Lu, Xuequan, Bittman, Robert, Futerman, Anthony H.
Wydane 2009

Chiral Vinylphosphonate and Phosphonate Analogues of the Immunosuppressive Agent FTY720

od Lu, Xuequan, Sun, Chaode, Valentine, William J., E, Shuyu, Liu, Jianxiong, Tigyi, Gabor, Bittman, Robert
Wydane 2009

Designed Semisynthetic Protein Inhibitors of Ub/Ubl E1 Activating Enzymes

od Lu, Xuequan, Olsen, Shaun K., Capili, Allan D., Cisar, Justin S., Lima, Christopher D., Tan, Derek S.
Wydane 2010

FTY720 Analogues as Sphingosine Kinase 1 Inhibitors: ENZYME INHIBITION KINETICS, ALLOSTERISM, PROTEASOMAL DEGRADATION, AND ACTIN REARRANGEMENT IN MCF-7 BREAST CANCER CELLS

od Lim, Keng G., Tonelli, Francesca, Li, Zaiguo, Lu, Xuequan, Bittman, Robert, Pyne, Susan, Pyne, Nigel J.
Wydane 2011

Stable Analogues of OSB-AMP: Potent Inhibitors of MenE, the o-Succinylbenzoate-CoA Synthetase from Bacterial Menaquinone Biosynthesis

od Lu, Xuequan, Zhou, Rong, Sharma, Indrajeet, Li, Xiaokai, Kumar, Gyanendra, Swaminathan, Subramanyam, Tonge, Peter J., Tan, Derek S.
Wydane 2011

Structural basis for adenylation and thioester bond formation in the ubiquitin E1

od Hann, Zachary S., Ji, Cheng, Olsen, Shaun K., Lu, Xuequan, Lux, Michaelyn C., Tan, Derek S., Lima, Christopher D.
Wydane w Proc Natl Acad Sci U S A (2019)

Mycobacterial PGL virulence factor biosynthesis: mechanism and small-molecule inhibition of polyketide chain initiation

od Ferreras, Julian A., Stirrett, Karen L., Lu, Xuequan, Ryu, Jae-Sang, Soll, Clifford E., Tan, Derek S., Quadri, Luis E. N.
Wydane 2007

FTY720 Inhibits Ceramide Synthases and Up-regulates Dihydrosphingosine 1-Phosphate Formation in Human Lung Endothelial Cells

od Berdyshev, Evgeny V., Gorshkova, Irina, Skobeleva, Anastasia, Bittman, Robert, Lu, Xuequan, Dudek, Steven M., Mirzapoiazova, Tamara, Garcia, Joe G. N., Natarajan, Viswanathan
Wydane 2009

Kinetic Analyses of the Siderophore Biosynthesis Inhibitor Salicyl-AMS and Analogues as MbtA Inhibitors and Antimycobacterial Agents

od Bythrow, Glennon V., Mohandas, Poornima, Guney, Tezcan, Standke, Lisa C., Germain, Gabrielle A., Lu, Xuequan, Ji, Cheng, Levendosky, Keith, Chavadi, Sivagami Sundaram, Tan, Derek S., Quadri, Luis E. N.
Wydane w Biochemistry (2019)

(S)-FTY720-Vinylphosphonate, an Analogue of the Immunosuppressive Agent FTY720, Is a Pan-antagonist of Sphingosine 1-Phosphate GPCR Signaling and Inhibits Autotaxin Activity

od Valentine, William J., Kiss, Gyöngyi N., Liu, Jianxiong, Shuyu, E, Gotoh, Mari, Murokami-Murofushi, Kimiko, Pham, Truc Chi, Baker, Daniel L., Parrill, Abby L., Lu, Xuequan, Sun, Chaode, Bittman, Robert, Pyne, Nigel J., Tigyi, Gabor
Wydane 2010