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Designed Semisynthetic Protein Inhibitors of Ub/Ubl E1 Activating Enzymes

[Image: see text] Semisynthetic, mechanism-based protein inhibitors of ubiquitin (Ub) and ubiquitin-like modifier (Ubl) activating enzymes (E1s) have been developed to target E1-catalyzed adenylation and thioesterification of the Ub/Ubl C-terminus during the processes of protein SUMOylation and ubiq...

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Detalhes bibliográficos
Main Authors: Lu, Xuequan, Olsen, Shaun K., Capili, Allan D., Cisar, Justin S., Lima, Christopher D., Tan, Derek S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830896/
https://ncbi.nlm.nih.gov/pubmed/20099854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja9088549
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