Increased Binding of Apolipoproteins A-I and E4 to Triglyceride-Rich Lipoproteins is linked to Induction of Hypertriglyceridemia

par Gorshkova, Irina N., Atkinson, David
Publié dans JSM Atheroscler (2017)

Enhanced Binding of Apolipoprotein A-I Variants Associated with Hypertriglyceridemia to Triglyceride-Rich Particles

par Gorshkova, Irina N., Atkinson, David
Publié dans Biochemistry (2011)

Binding of human apoA-I[K107del] variant to TG-rich particles: implications for mechanisms underlying hypertriglyceridemia

par Gorshkova, Irina N., Mei, Xiaohu, Atkinson, David
Publié dans J Lipid Res (2014)

Arginine 123 of apolipoprotein A-I is essential for lecithin:cholesterol acyltransferase activity

par Gorshkova, Irina N., Mei, Xiaohu, Atkinson, David
Publié dans J Lipid Res (2018)

Biophysical Properties of Apolipoprotein E4 Variants: Implications in Molecular Mechanisms of Correction of Hypertriglyceridemia

par Gorshkova, Irina N., Kypreos, Kyriakos E., Gantz, Donald L., Zannis, Vassilis I., Atkinson, David
Publié 2008

Regulation of NADPH Oxidase in Vascular Endothelium: The Role of Phospholipases, Protein Kinases, and Cytoskeletal Proteins

par Pendyala, Srikanth, Usatyuk, Peter V., Gorshkova, Irina A., Garcia, Joe G.N., Natarajan, Viswanathan
Publié 2009

Multiple sphingolipid abnormalities following cerebral microendothelial hypoxia

par Testai, Fernando D., Kilkus, John P., Berdyshev, Evgeny, Gorshkova, Irina, Natarajan, Viswanathan, Dawson, Glyn
Publié dans J Neurochem (2014)

Structure and Stability of Apolipoprotein A-I in Solution and in Discoidal High Density Lipoprotein Probed by Double Charge Ablation and Deletion Mutation

par Gorshkova, Irina N., Liu, Tong, Kan, Horng-Yuan, Chroni, Angeliki, Zannis, Vassilis I., Atkinson, David
Publié 2006

Alteration of negatively charged residues in the 89 to 99 domain of apoA-I affects lipid homeostasis and maturation of HDL

par Kateifides, Andreas K., Gorshkova, Irina N., Duka, Adelina, Chroni, Angeliki, Kardassis, Dimitris, Zannis, Vassilis I.
Publié 2011

Lysophosphatidic acid-induced transactivation of epidermal growth factor receptor regulates cyclo-oxygenase-2 expression and prostaglandin E(2) release via C/EBPβ in human bronchia...

par HE, Donghong, NATARAJAN, Viswanathan, STERN, Randi, GORSHKOVA, Irina A., SOLWAY, Julian, SPANNHAKE, Ernst Wm., ZHAO, Yutong
Publié 2008

Characterization of sphingosine-1-phosphate lyase activity by ESI-LC/MS/MS quantitation of (2E)-hexadecenal

par Berdyshev, Evgeny V., Goya, Jonathan, Gorshkova, Irina, Prestwich, Glenn D., Byun, Hoe-Sup, Bittman, Robert, Natarajan, Viswanathan
Publié 2010

Dynamin 2 and c-Abl Are Novel Regulators of Hyperoxia-mediated NADPH Oxidase Activation and Reactive Oxygen Species Production in Caveolin-enriched Microdomains of the Endothelium

par Singleton, Patrick A., Pendyala, Srikanth, Gorshkova, Irina A., Mambetsariev, Nurbek, Moitra, Jaideep, Garcia, Joe G. N., Natarajan, Viswanathan
Publié 2009

Phospholipase D-mediated Activation of IQGAP1 through Rac1 Regulates Hyperoxia-induced p47(phox) Translocation and Reactive Oxygen Species Generation in Lung Endothelial Cells

par Usatyuk, Peter V., Gorshkova, Irina A., He, Donghong, Zhao, Yutong, Kalari, Satish K., Garcia, Joe G. N., Natarajan, Viswanathan
Publié 2009

Photolysis of caged sphingosine-1-phosphate induces barrier enhancement and intracellular activation of lung endothelial cell signaling pathways

par Usatyuk, Peter V., He, Donghong, Bindokas, Vytas, Gorshkova, Irina A., Berdyshev, Evgeny V., Garcia, Joe G. N., Natarajan, Viswanathan
Publié 2011

Changes in the Metabolism of Sphingolipids after Subarachnoid Hemorrhage

par Testai, Fernando D, Xu, Hao-Liang, Kilkus, John, Suryadevara, Vidyani, Gorshkova, Irina, Berdyshev, Evgeny, Pelligrino, Dale A, Dawson, Dawson
Publié dans J Neurosci Res (2015)

Role of Nox4 and Nox2 in Hyperoxia-Induced Reactive Oxygen Species Generation and Migration of Human Lung Endothelial Cells

par Pendyala, Srikanth, Gorshkova, Irina A, Usatyuk, Peter V., He, Donghong, Pennathur, Arjun, Lambeth, J. David, Thannickal, Victor J., Natarajan, Viswanathan
Publié 2009

Docosatetraenoyl LPA is elevated in exhaled breath condensate in idiopathic pulmonary fibrosis

par Montesi, Sydney B, Mathai, Susan K, Brenner, Laura N, Gorshkova, Irina A, Berdyshev, Evgeny V, Tager, Andrew M, Shea, Barry S
Publié 2014

The Roles of Sphingosine Kinase 1 and 2 in Regulating the Metabolome and Survival of Prostate Cancer Cells

par Tonelli, Francesca, Alossaimi, Manal, Natarajan, Viswanathan, Gorshkova, Irina, Berdyshev, Evgeny, Bittman, Robert, Watson, David G., Pyne, Susan, Pyne, Nigel J
Publié 2013

Akt activates NOS3 and separately restores barrier integrity in H(2)O(2)-stressed human cardiac microvascular endothelium

par Dossumbekova, Anar, Berdyshev, Evgeny V., Gorshkova, Irina, Shao, Zuohui, Li, Changqing, Long, Phillip, Joshi, Atul, Natarajan, Viswanathan, Vanden Hoek, Terry L.
Publié 2008

FTY720 Inhibits Ceramide Synthases and Up-regulates Dihydrosphingosine 1-Phosphate Formation in Human Lung Endothelial Cells

par Berdyshev, Evgeny V., Gorshkova, Irina, Skobeleva, Anastasia, Bittman, Robert, Lu, Xuequan, Dudek, Steven M., Mirzapoiazova, Tamara, Garcia, Joe G. N., Natarajan, Viswanathan
Publié 2009