Photolysis of caged sphingosine-1-phosphate induces barrier enhancement and intracellular activation of lung endothelial cell signaling pathways

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid that mediates cellular functions by ligation via G protein-coupled S1P receptors. In addition to its extracellular action, S1P also has intracellular effects; however, the signaling pathways modulated by intracellular S1P remain poorly define...

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Main Authors: Usatyuk, Peter V., He, Donghong, Bindokas, Vytas, Gorshkova, Irina A., Berdyshev, Evgeny V., Garcia, Joe G. N., Natarajan, Viswanathan
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119122/
https://ncbi.nlm.nih.gov/pubmed/21478254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00404.2010
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