Intracellular Generation of Sphingosine 1-Phosphate in Human Lung Endothelial Cells: ROLE OF LIPID PHOSPHATE PHOSPHATASE-1 AND SPHINGOSINE KINASE 1

Sphingosine 1-phosphate (S1P) regulates diverse cellular functions through extracellular ligation to S1P receptors, and it also functions as an intracellular second messenger. Human pulmonary artery endothelial cells (HPAECs) effectively utilized exogenous S1P to generate intracellular S1P. We, ther...

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Hauptverfasser: Zhao, Yutong, Kalari, Satish K., Usatyuk, Peter V., Gorshkova, Irina, He, Donghong, Watkins, Tonya, Brindley, David N., Sun, Chaode, Bittman, Robert, Garcia, Joe G. N., Berdyshev, Evgeni V., Natarajan, Viswanathan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659598/
https://ncbi.nlm.nih.gov/pubmed/17379599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M701279200
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