Hyaluronan Regulation of Endothelial Barrier Function in Cancer

Por Singleton, Patrick A.
Publicado no Adv Cancer Res (2014)

Role of hyaluronan and hyaluronan-binding proteins in lung pathobiology

Por Lennon, Frances E., Singleton, Patrick A.
Publicado em 2011

Hyaluronan regulation of vascular integrity

Por Lennon, Frances E, Singleton, Patrick A
Publicado em 2011

Acute Lung Injury Regulation by Hyaluronan

Por Singleton, Patrick A., Lennon, Frances E.
Publicado em 2011

Calcium-induced Human Keratinocyte Differentiation Requires src- and fyn-mediated Phosphatidylinositol 3-Kinase–dependent Activation of Phospholipase C-γ1

Por Xie, Zhongjian, Singleton, Patrick A., Bourguignon, Lilly Y.W., Bikle, Daniel D.
Publicado em 2005

Transactivation of the Receptor-tyrosine Kinase Ephrin Receptor A2 Is Required for the Low Molecular Weight Hyaluronan-mediated Angiogenesis That Is implicated in Tumor Progression

Por Lennon, Frances E, Mirzapoiazova, Tamara, Mambetsariev, Nurbek, Mambetsariev, Bolot, Salgia, Ravi, Singleton, Patrick A.
Publicado em 2014

PHOSPHOTYROSINE PROTEIN DYNAMICS IN CELL MEMBRANE RAFTS OF SPHINGOSINE-1-PHOSPHATE-STIMULATED HUMAN ENDOTHELIUM: ROLE IN BARRIER ENHANCEMENT

Por Zhao, Jing, Singleton, Patrick A., Brown, Mary E., Dudek, Steven M., Garcia, Joe G.N.
Publicado em 2009

The Mu Opioid Receptor Promotes Opioid and Growth Factor-Induced Proliferation, Migration and Epithelial Mesenchymal Transition (EMT) in Human Lung Cancer

Por Lennon, Frances E., Mirzapoiazova, Tamara, Mambetsariev, Bolot, Poroyko, Valeriy A., Salgia, Ravi, Moss, Jonathan, Singleton, Patrick A.
Publicado em 2014

HABP2 is a Novel Regulator of Hyaluronan-Mediated Human Lung Cancer Progression

Por Mirzapoiazova, Tamara, Mambetsariev, Nurbek, Lennon, Frances E., Mambetsariev, Bolot, Berlind, Joshua E., Salgia, Ravi, Singleton, Patrick A.
Publicado no Front Oncol (2015)

Extracellular Vesicles from Caveolin-Enriched Microdomains Regulate Hyaluronan-Mediated Sustained Vascular Integrity

Por Mirzapoiazova, Tamara, Lennon, Frances E., Mambetsariev, Bolot, Allen, Michael, Riehm, Jacob, Poroyko, Valeriy A., Singleton, Patrick A.
Publicado no Int J Cell Biol (2015)

Dynamin 2 and c-Abl Are Novel Regulators of Hyperoxia-mediated NADPH Oxidase Activation and Reactive Oxygen Species Production in Caveolin-enriched Microdomains of the Endothelium

Por Singleton, Patrick A., Pendyala, Srikanth, Gorshkova, Irina A., Mambetsariev, Nurbek, Moitra, Jaideep, Garcia, Joe G. N., Natarajan, Viswanathan
Publicado em 2009

High-molecular-weight hyaluronan is a novel inhibitor of pulmonary vascular leakiness

Por Singleton, Patrick A., Mirzapoiazova, Tamara, Guo, Yurong, Sammani, Saad, Mambetsariev, Nurbek, Lennon, Frances E., Moreno-Vinasco, Liliana, Garcia, Joe G. N.
Publicado em 2010

Methylnaltrexone Potentiates the Anti-Angiogenic Effects of mTOR Inhibitors

Por Singleton, Patrick A, Mambetsariev, Nurbek, Lennon, Frances E, Mathew, Biji, Siegler, Jessica H, Moreno-Vinasco, Liliana, Salgia, Ravi, Moss, Jonathan, Garcia, Joe GN
Publicado em 2010

Critical Role of S1PR1 and Integrin β4 in HGF/c-Met-mediated Increases in Vascular Integrity

Por Ephstein, Yulia, Singleton, Patrick A., Chen, Weiguo, Wang, Lichun, Salgia, Ravi, Kanteti, Prasad, Dudek, Steven M., Garcia, Joe G. N., Jacobson, Jeffrey R.
Publicado em 2013

Quantitative Proteomics Analysis of Human Endothelial Cell Membrane Rafts: EVIDENCE OF MARCKS AND MRP REGULATION IN THE SPHINGOSINE 1-PHOSPHATE-INDUCED BARRIER ENHANCEMENT

Por Guo, Yurong, Singleton, Patrick A., Rowshan, Austin, Gucek, Marjan, Cole, Robert N., Graham, David R. M., Van Eyk, Jennifer E., Garcia, Joe G. N.
Publicado em 2007

Akt-Mediated Transactivation of the S1P(1) Receptor in Caveolin-Enriched Microdomains Regulates Endothelial Barrier Enhancement by Oxidized Phospholipids

Por Singleton, Patrick A., Chatchavalvanich, Santipongse, Fu, Panfeng, Xing, Junjie, Birukova, Anna A., Fortune, Jennifer A., Klibanov, Alexander M., Garcia, Joe G. N., Birukov, Konstantin G.
Publicado em 2009

GRP78 is a novel receptor initiating a vascular barrier protective response to oxidized phospholipids

Por Birukova, Anna A., Singleton, Patrick A., Gawlak, Grzegorz, Tian, Xinyong, Mirzapoiazova, Tamara, Mambetsariev, Bolot, Dubrovskyi, Oleksii, Oskolkova, Olga V., Bochkov, Valery N., Birukov, Konstantin G.
Publicado em 2014

Novel Role for Non-muscle Myosin Light Chain Kinase (MLCK) in Hyperoxia-induced Recruitment of Cytoskeletal Proteins, NADPH Oxidase Activation, and Reactive Oxygen Species Generati...

Por Usatyuk, Peter V., Singleton, Patrick A., Pendyala, Srikanth, Kalari, Satish K., He, Donghong, Gorshkova, Irina A., Camp, Sara M., Moitra, Jaideep, Dudek, Steven M., Garcia, Joe G. N., Natarajan, Viswanathan
Publicado em 2012

EphA2 Mutation in Lung Squamous Cell Carcinoma Promotes Increased Cell Survival, Cell Invasion, Focal Adhesions, and Mammalian Target of Rapamycin Activation

Por Faoro, Leonardo, Singleton, Patrick A., Cervantes, Gustavo M., Lennon, Frances E., Choong, Nicholas W., Kanteti, Rajani, Ferguson, Benjamin D., Husain, Aliya N., Tretiakova, Maria S., Ramnath, Nithya, Vokes, Everett E., Salgia, Ravi
Publicado em 2010

GADD45a is a novel candidate gene in inflammatory lung injury via influences on Akt signaling

Por Meyer, Nuala J., Huang, Yong, Singleton, Patrick A., Sammani, Saad, Moitra, Jaideep, Evenoski, Carrie L., Husain, Aliya N., Mitra, Sumegha, Moreno-Vinasco, Liliana, Jacobson, Jeffrey R., Lussier, Yves A., Garcia, Joe G. N.
Publicado em 2009