Statins as a novel therapeutic strategy in acute lung injury

Por Singla, Sunit, Jacobson, Jeffrey R.
Publicado em 2012

Endothelial FAK as a Therapeutic Target in Disease

Por Infusino, Giovanni A., Jacobson, Jeffrey R.
Publicado em 2011

Activation of NFkB and coagulation in lung injury by hyperoxia and excessive mechanical ventilation: one more reason “low and slow” is the way to go?

Por Jacobson, Jeffrey R., Birukov, Konstantin G.
Publicado em 2009

Integrin β4 Attenuates SHP-2 and MAPK Signaling and Reduces Human Lung Endothelial Inflammatory Responses

Por Chen, Weiguo, Garcia, Joe G.N., Jacobson, Jeffrey R.
Publicado em 2010

MicroRNA Regulation of Integrins

Por Chen, Weiguo, Harbeck, Mark, Zhang, Wei, Jacobson, Jeffrey R.
Publicado em 2013

Treating the Host Response to Ebola Virus Disease with Generic Statins and Angiotensin Receptor Blockers

Por Fedson, David S., Jacobson, Jeffrey R., Rordam, Ole Martin, Opal, Steven M.
Publicado no mBio (2015)

Reply to “Generic Statins and Angiotensin Receptor Blockers: Are They Really Useful in Ebola?”

Por Fedson, David S., Jacobson, Jeffrey R., Rordam, Ole Martin, Opal, Steven M.
Publicado no mBio (2016)

Endothelial cell barrier protection by simvastatin: GTPase regulation and NADPH oxidase inhibition

Por Chen, Weiguo, Pendyala, Srikanth, Natarajan, Viswanathan, Garcia, Joe G. N., Jacobson, Jeffrey R.
Publicado em 2008

Critical role for integrin-β4 in the attenuation of murine acute lung injury by simvastatin

Por Chen, Weiguo, Sammani, Saad, Mitra, Sumegha, Ma, Shwu Fan, Garcia, Joe G. N., Jacobson, Jeffrey R.
Publicado em 2012

Prostaglandins PGE(2) and PGI(2) promote endothelial barrier enhancement via PKA- and Epac1/Rap1-dependent Rac activation

Por Birukova, Anna A., Zagranichnaya, Tatiana, Fu, Panfeng, Alekseeva, Elena, Chen, Weiguo, Jacobson, Jeffrey R., Birukov, Konstantin G.
Publicado em 2007

Role of Claudin-5 in the Attenuation of Murine Acute Lung Injury by Simvastatin

Por Chen, Weiguo, Sharma, Rajesh, Rizzo, Alicia N., Siegler, Jessica H., Garcia, Joe G. N., Jacobson, Jeffrey R.
Publicado em 2014

Interaction of Integrin β4 with S1P Receptors in S1P- and HGF-Induced Endothelial Barrier Enhancement()

Por Ni, Xiuqin, Epsthein, Yulia, Chen, Weiguo, Zhou, Tingting, Xie, Lishi, Garcia, Joe G.N., Jacobson, Jeffrey R.
Publicado no J Cell Biochem (2014)

Role of Integrin β4 in Lung Endothelial Cell Inflammatory Responses to Mechanical Stress

Por Chen, Weiguo, Epshtein, Yulia, Ni, Xiuquin, Dull, Randal O., Cress, Anne E., Garcia, Joe G.N., Jacobson, Jeffrey R.
Publicado no Sci Rep (2015)

Imatinib attenuates inflammation and vascular leak in a clinically relevant two-hit model of acute lung injury

Por Rizzo, Alicia N., Sammani, Saad, Esquinca, Adilene E., Jacobson, Jeffrey R., Garcia, Joe G. N., Letsiou, Eleftheria, Dudek, Steven M.
Publicado no Am J Physiol Lung Cell Mol Physiol (2015)

GADD45a Promoter Regulation by a Functional Genetic Variant Associated with Acute Lung Injury

Por Mitra, Sumegha, Wade, Michael S., Sun, Xiaoguang, Moldobaeva, Nurgul, Flores, Carlos, Ma, Shwu-Fan, Zhang, Wei, Garcia, Joe G. N., Jacobson, Jeffrey R.
Publicado em 2014

Critical Role of S1PR1 and Integrin β4 in HGF/c-Met-mediated Increases in Vascular Integrity

Por Ephstein, Yulia, Singleton, Patrick A., Chen, Weiguo, Wang, Lichun, Salgia, Ravi, Kanteti, Prasad, Dudek, Steven M., Garcia, Joe G. N., Jacobson, Jeffrey R.
Publicado em 2013

Role of Growth Arrest and DNA Damage–inducible α in Akt Phosphorylation and Ubiquitination after Mechanical Stress-induced Vascular Injury

Por Mitra, Sumegha, Sammani, Saad, Wang, Ting, Boone, David L., Meyer, Nuala J., Dudek, Steven M., Moreno-Vinasco, Liliana, Garcia, Joe G. N., Jacobson, Jeffrey R.
Publicado em 2011

Krüppel Like Factor 4 Promoter Undergoes Active Demethylation during Monocyte/Macrophage Differentiation

Por Karpurapu, Manjula, Ranjan, Ravi, Deng, Jing, Chung, Sangwoon, Lee, Yong Gyu, Xiao, Lei, Nirujogi, Teja Srinivas, Jacobson, Jeffrey R., Park, Gye Young, Christman, John W
Publicado em 2014

Nonmuscle myosin light chain kinase activity modulates radiation-induced lung injury

Por Wang, Ting, Mathew, Biji, Wu, Xiaomin, Shimizu, Yuka, Rizzo, Alicia N., Dudek, Steven M., Weichselbaum, Ralph R., Jacobson, Jeffrey R., Hecker, Louise, Garcia, Joe G. N.
Publicado no Pulm Circ (2016)

Role of GADD45a in murine models of radiation- and bleomycin-induced lung injury

Por Mathew, Biji, Takekoshi, Daisuke, Sammani, Saad, Epshtein, Yulia, Sharma, Rajesh, Smith, Brett D., Mitra, Sumegha, Desai, Ankit A., Weichselbaum, Ralph R., Garcia, Joe G. N., Jacobson, Jeffrey R.
Publicado no Am J Physiol Lung Cell Mol Physiol (2015)