GADD45a Promoter Regulation by a Functional Genetic Variant Associated with Acute Lung Injury

RATIONALE: Growth arrest DNA damage inducible alpha (GADD45a) is a stress-induced gene we have shown to participate in the pathophysiology of ventilator-induced lung injury (VILI) via regulation of mechanical stress-induced Akt ubiquitination and phosphorylation. The regulation of GADD45a expression...

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Bibliographic Details
Main Authors: Mitra, Sumegha, Wade, Michael S., Sun, Xiaoguang, Moldobaeva, Nurgul, Flores, Carlos, Ma, Shwu-Fan, Zhang, Wei, Garcia, Joe G. N., Jacobson, Jeffrey R.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062486/
https://ncbi.nlm.nih.gov/pubmed/24940746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100169
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