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Critical role for integrin-β4 in the attenuation of murine acute lung injury by simvastatin

The statins are a class of 3-hydroxy-3-methylglutaryl-coenzyme A-reductase inhibitors that are recognized to have pleiotropic properties. We previously reported the attenuation of LPS-induced murine acute lung injury (ALI) by simvastatin in vivo and identified relevant effects of simvastatin on endo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Weiguo, Sammani, Saad, Mitra, Sumegha, Ma, Shwu Fan, Garcia, Joe G. N., Jacobson, Jeffrey R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423831/
https://ncbi.nlm.nih.gov/pubmed/22683568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00361.2011
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